What is the typical range for normal serum alkaline phosphatase activity?
Answer
(B)
5.0-13.0 KA units/100 ml
2
Which measurement is most indicative of early myocardial ischemia?
Answer
(A)
CPK
3
Which condition is associated with elevated serum acid phosphatase levels?
Answer
(A)
Metastatic carcinoma of prostate
4
Which of the following is linked to increased serum alkaline phosphatase levels?
Answer
(C)
Hyperparathyroidism
5
Which medical condition is often accompanied by a rise in serum lipase levels?
Answer
(C)
Acute pancreatitis
6
Which condition is characterized by a reduction in serum ferroxidase levels?
Answer
(D)
Wilson's disease
7
In which of the following is the LDH isoenzyme often elevated?
Answer
(C)
Liver disease
8
Which enzyme is typically elevated on the third day after the onset of an acute myocardial infarction?
Answer
(C)
Serum LDH
9
Which condition often sees elevated levels of LDH1 and LDH2?
Answer
(A)
Myocardial infarction
10
Which CK isoenzymes are found in cardiac muscle?
Answer
(B)
MM and MB
11
In the early stages of acute inflammation of the pancreas, which enzyme typically shows an elevated level within the initial five days?
Answer
(A)
Serum amylase
12
What is a key characteristic of acute pancreatitis related to enzyme activity?
Answer
(C)
Zymogen enzymes becoming active too early
13
Which of the following enzymes found in plasma serves a specific physiological function?
Answer
(A)
Lipoprotein lipase
14
Which enzyme, present in the plasma, does not have a primary function in the plasma itself?
Answer
(D)
Lipase
15
What is the ideal pH range for salivary amylase to function most effectively?
Answer
(A)
6.6-6.8
16
What is the optimal pH for pancreatic amylase activity?
Answer
(D)
8.6
17
At what pH does sucrase demonstrate the highest level of activity?
Answer
(A)
5.0-7.0
18
What pH range is most conducive for maltase to perform its function efficiently?
Answer
(C)
5.8-6.2
19
What is the optimal pH range for lactase activity?
Answer
(B)
5.4-6.0
20
Which of the following substances acts as the primary target for amylase?
Answer
(B)
Starch
21
Which ion plays a crucial role in enabling the function of salivary amylase?
Answer
(A)
Chloride
22
What substance enhances the activity of pancreatic amylase?
Answer
(B)
Bile salts
23
Which of the following carbohydrates is indigestible in the human digestive system?
Answer
(A)
Cellulose
24
What type of sugar uptake relies on facilitated diffusion, employing a Na-independent transporter?
Answer
(B)
Fructose
25
In the small intestine, which pair of sugars experiences the highest absorption rate?
Answer
(A)
Glucose and galactose
26
What vitamin is known to enhance the absorption of glucose?
Answer
(B)
Thiamin
27
Which hormone directly influences the intestinal lining, thereby stimulating the absorption of glucose?
Answer
(C)
Thyroxine
28
Given the provided information about ATP and Glucose 6-phosphate hydrolysis, calculate the standard free energy change (AG°) for the phosphorylation of glucose: Glucose + ATP → Glucose 6-Phosphate + ADP.
Answer
(C)
-4.0 Kcal/mol
29
When blood glucose levels are low, the brain, unlike the liver, can still absorb glucose. This difference is attributed to the
Answer
(A)
Low K of hexokinase
30
In the chemical reaction: NuTP + glucose → Glucose 6-Phosphate + NuDP, what does 'NuTP' represent?
Answer
(A)
ATP
31
Referring to the provided diagrams, where is fructose 1,6-biphosphate located?
Answer
(C)
C
32
Which glycolytic enzyme is susceptible to fluoride ion inhibition?
Answer
(C)
Enolase
33
In glycolysis, which enzyme's function is disrupted by iodoacetate?
Answer
(B)
Glyceraldehyde-3-phosphate dehydrogenase
34
What enzyme catalyzes the conversion of enolpyruvate to ketopyruvate in the glycolytic pathway?
Answer
(D)
Spontaneously
35
In red blood cells, what intermediate is the precursor to 2,3-biphosphoglycerate?
Answer
(B)
1, 3-Biphosphoglycerate
36
High concentrations of 2,3-biphosphoglycerate interacting with hemoglobin result in what effect on the oxyhemoglobin dissociation curve?
Answer
(B)
Displacement of the oxyhemoglobin dissociation curve to the right
37
Which of the following compounds can accumulate in erythrocytes under normal circumstances and in anaerobic microorganisms?
Answer
(D)
Lactate
38
Which enzyme(s) involved in glycolysis contribute to the high-energy phosphorylation of substrates?
Answer
(D)
Glyceraldehyde-3-phosphate dehydrogenase
39
The Lineweaver-Burk plot is used to analyze which of the following factors?
Answer
(D)
Both (A) and (B)
40
Which of the following substances inhibits the activity of phosphofructokinase, a key enzyme in glycolysis?
Answer
(A)
Citrate and ATP
41
Which enzyme plays a role in controlling the rate of glycolysis?
Answer
(A)
Phosphofructokinase
42
Hexokinase's function is reduced through which of the following mechanisms?
Answer
(A)
Glucose-6-Phosphate
43
Which of the following processes involves the rearrangement of molecular structure?
Answer
(A)
Glucose 6-Phosphate fructose 6 phosphate
44
What is the overall yield of ATP molecules from one glucose molecule in the absence of oxygen during glycolysis?
Answer
(B)
2
45
The multi-enzyme complex involved in converting pyruvate is essential for creating
Answer
(A)
Acetyl-CoA
46
A lack of thiamin in the diet negatively affects which enzyme's function?
Answer
(B)
Pyruvate dehydrogenase
47
Which substance reduces the activity of the enzyme that processes pyruvate?
Answer
(A)
Mercury
48
In a typical human at rest, what organ or tissue utilizes the majority of the glucose in the blood?
Answer
(A)
Liver
49
Where are the enzymes of the glycolysis pathway primarily located within the cell?
Answer
(A)
Extramitochondrial soluble fraction of the cell
50
Considering metabolic pathways as primarily building up or breaking down, which one is best described as having both characteristics?
