Quick Biochemistry - Nucleic Acids (Section 1)

  • 1
    What components combine to form a nucleoside?
    Trả lời
    (B)
    A purine or pyrimidine base and a sugar
  • 2
    Which of the following best describes the composition of a nucleotide?
    Trả lời
    (B)
    A purine and pyrimidine base, a sugar, and phosphorous
  • 3
    Which of the following is classified as a purine nucleotide?
    Trả lời
    (A)
    AMP
  • 4
    Which option represents a pyrimidine nucleotide?
    Trả lời
    (C)
    CMP
  • 5
    Adenine is also known as:
    Trả lời
    (A)
    6-Amino purine
  • 6
    What is the other name for 2, 4-Dioxypyrimidine?
    Trả lời
    (C)
    Uracil
  • 7
    What is the chemical designation for guanine?
    Trả lời
    (B)
    2-Amino-6-oxypurine
  • 8
    In what units are the concentrations of nucleotides and nucleic acids frequently expressed?
    Trả lời
    (D)
    OD at 260 nm
  • 9
    Which pyrimidine nucleotide is involved in high-energy intermediate reactions?
    Trả lời
    (C)
    UDPG
  • 10
    In a nucleotide, what carbon position on the pentose molecule is involved in an ester bond with phosphate?
    Trả lời
    (D)
    C₅
  • 11
    What molecule results from the combination of uracil and ribose?
    Trả lời
    (A)
    Uridine
  • 12
    Which nucleotide is most prevalent in a free state within animal cells?
    Trả lời
    (A)
    ATP
  • 13
    Approximately what is the average intracellular concentration of ATP in a mammalian cell?
    Trả lời
    (A)
    1 mM
  • 14
    Which base is present in messenger RNA but absent in deoxyribonucleic acid?
    Trả lời
    (D)
    Uracil
  • 15
    What is the function of 'Caps' in an RNA molecule?
    Trả lời
    (B)
    Are unique to eukaryotic mRNA
  • 16
    How does prokaryotic mRNA differ from eukaryotic mRNA?
    Trả lời
    (A)
    Can be polycistronic
  • 17
    What is the approximate size range of small stable RNA molecules?
    Trả lời
    (C)
    90-300 nucleotides
  • 18
    What is the approximate range of small stable RNAs found within a single cell?
    Trả lời
    (C)
    1,00,000-10,00,000
  • 19
    What is the approximate molecular weight of heterogenous nuclear RNA (hnRNA)?
    Trả lời
    (A)
    More than 107
  • 20
    In RNA, why isn't the guanine content always equal to cytosine, and adenine always equal to uracil?
    Trả lời
    (A)
    Single strand molecule
  • 21
    Which nitrogenous base is found in RNA?
    Trả lời
    (B)
    Uracil
  • 22
    Which of the following is NOT a component of RNA?
    Trả lời
    (C)
    Thymine
  • 23
    What type of sugar is found in RNA?
    Trả lời
    (C)
    Ribose
  • 24
    Which statement accurately describes base pairing in an RNA molecule?
    Trả lời
    (D)
    Guanine content does not necessarily equal its cytosine content.
  • 25
    In which type of RNA are methylated purines and pyrimidines typically found?
    Trả lời
    (C)
    tRNA
  • 26
    Where is Thymine typically found?
    Trả lời
    (A)
    tRNA
  • 27
    What is the approximate number of nucleotides in a tRNA molecule?
    Trả lời
    (C)
    75
  • 28
    In a typical cell, what is the minimum number of different tRNA molecules present?
    Trả lời
    (B)
    20
  • 29
    What shape does a tRNA molecule resemble?
    Trả lời
    (C)
    Clover leaf
  • 30
    In tRNA molecules, the CCA sequence is always located at the:
    Trả lời
    (A)
    3' Termini
  • 31
    What is the basis for classifying Transfer RNAs?
    Trả lời
    (D)
    Extra arm
  • 32
    Which modified base is found in the D arm of a tRNA molecule, giving it its name?
    Trả lời
    (A)
    Uridine
  • 33
    How many base pairs are typically found in the acceptor arm of a tRNA molecule?
    Trả lời
    (B)
    7 Base pairs
  • 34
    How many base pairs does the anticodon arm of a tRNA molecule typically possess?
    Trả lời
    (A)
    5 Base pairs
  • 35
    What sequence is typically found in the TΨC arm of a tRNA molecule?
    Trả lời
    (A)
    T, pseudouridine and C
  • 36
    Who put forth the double helical structure model of DNA?
    Trả lời
    (C)
    Watson and Crick
  • 37
    Which of the following is NOT found in DNA?
    Trả lời
    (C)
    Uracil
  • 38
    What is the type of sugar molecule found in DNA?
    Trả lời
    (A)
    Deoxyribose
  • 39
    DNA segments with a high concentration of A-T pairs are stabilized by how many hydrogen bonds?
    Trả lời
    (B)
    2 Hydrogen bonds
  • 40
    Which statement accurately describes the base composition in a DNA molecule?
    Trả lời
    (D)
    Guanine content equals cytosine content
  • 41
    DNA with a high proportion of G-C pairs tend to have what characteristic regarding hydrogen bonds?
    Trả lời
    (C)
    3 Hydrogen bonds
  • 42
    Given that DNA carries an organism's genetic code, what can be logically inferred about its base composition across different tissues?
    Trả lời
    (C)
    DNA from different tissues in the same organism should usually have the same base composition
  • 43
    What is the approximate width of the B-form DNA double helix in nanometers?
    Trả lời
    (B)
    2
  • 44
    How many base pairs are typically found in a single complete turn of the B-form DNA molecule?
    Trả lời
    (C)
    10
  • 45
    What is the distance, in nanometers, covered by one full turn of B-form DNA?
    Trả lời
    (D)
    3.4 nm
  • 46
    If the thymine concentration in a DNA molecule is 30%, what is the predicted concentration of guanosine?
    Trả lời
    (B)
    20%
  • 47
    If the guanosine content in a DNA molecule is 40%, what would be the percentage of adenine?
    Trả lời
    (A)
    10%
  • 48
    What factor leads to a higher melting temperature in duplex DNA?
    Trả lời
    (C)
    Cytosine + Guanine
  • 49
    What condition is often treated with the synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine?
    Trả lời
    (B)
    Gout
  • 50
    Which synthetic nucleotide analogue is frequently used in cancer and viral infection treatment?
    Trả lời
    (A)
    Arabinosyl cytosine