Quick Biochemistry - Hormone Metabolism (Section 6)

  • 1
    When catecholamines attach to αadrenergic receptors, what is the effect on intracellular cAMP levels?
    Відповідь
    (C)
    Lowers intracellular cAMP
  • 2
    Upon binding catecholamines, which receptor initiates the phosphoinositide cascade?
    Відповідь
    (A)
    α₁-Adrenergic receptors
  • 3
    Which metabolic process is reduced by the presence of epinephrine?
    Відповідь
    (A)
    Glycogenesis
  • 4
    Epinephrine elevates the level of free fatty acids in blood by stimulating which process?
    Відповідь
    (D)
    Lipolysis in fat cells
  • 5
    Which of the following is not increased by epinephrine?
    Відповідь
    (C)
    Glucose production in muscles
  • 6
    In which medical condition is catecholamine secretion elevated?
    Відповідь
    (C)
    Phaeochromocytoma
  • 7
    What type of hormones are produced by the adrenal cortex's zona glomerulosa?
    Відповідь
    (A)
    Glucocorticoids
  • 8
    What type of hormone is cortisol?
    Відповідь
    (B)
    Mineralocorticoid
  • 9
    Which hormone is the main mineralocorticoid?
    Відповідь
    (C)
    Aldactone A
  • 10
    Which of the following tissues does not synthesize steroid hormones?
    Відповідь
    (A)
    Testes
  • 11
    What molecule serves as the precursor for the synthesis of steroid hormones?
    Відповідь
    (A)
    Cholesterol
  • 12
    Which of the following compounds is a shared component in the production of all steroid hormones?
    Відповідь
    (A)
    Pregnenolone
  • 13
    Which compound acts as a shared intermediate in the production of both cortisol and aldosterone?
    Відповідь
    (A)
    Progesterone
  • 14
    What is a common precursor in the production of estrogens?
    Відповідь
    (B)
    Andostenedione
  • 15
    How are glucocorticoids primarily transported in the bloodstream?
    Відповідь
    (D)
    All of these
  • 16
    Which of the following statements regarding transcortin is false?
    Відповідь
    (C)
    It transports aldosterone
  • 17
    What is the mechanism of action of glucocorticoids in terms of secondary messengers?
    Відповідь
    (D)
    No second messenger is required
  • 18
    Which of the following processes is NOT increased by glucocorticoids?
    Відповідь
    (C)
    Synthesis of eicosanoids
  • 19
    Which of the following is NOT a product of glucocorticoid-stimulated synthesis?
    Відповідь
    (A)
    Glucokinase
  • 20
    The release of glucocorticoids is regulated by all EXCEPT:
    Відповідь
    (C)
    Feedback control by blood glucose
  • 21
    What effect does an overproduction of glucocorticoids have on blood sugar levels, and how is this effect achieved?
    Відповідь
    (C)
    Raising sugar levels by stimulating new sugar creation
  • 22
    Which of the following substances is *not* primarily regulated by mineralocorticoids in the body's metabolic processes?
    Відповідь
    (C)
    A non-metal element commonly found in table salt
  • 23
    Mineralocorticoids influence kidney function by boosting the reuptake of which substances from the tubules?
    Відповідь
    (C)
    An element found in salt and a non-metal element found in salt
  • 24
    Mineralocorticoids influence kidney function by boosting the release of which substances into the tubules?
    Відповідь
    (B)
    An element involved in nerve function
  • 25
    Which of the following factors stimulates the release of mineralocorticoids?
    Відповідь
    (B)
    A protein involved in blood pressure regulation
  • 26
    What electrolyte imbalance is associated with Addison's disease, where the body retains too much of it?
    Відповідь
    (A)
    An element involved in nerve function
  • 27
    In a condition resulting from a complete absence of an enzyme in the adrenal cortex, what are the key hormonal imbalances observed?
    Відповідь
    (D)
    All of the above
  • 28
    What is the primary function of spironolactone in relation to other hormones?
    Відповідь
    (C)
    It blocks a steroid hormone that controls electrolyte balance
  • 29
    Where are androgens primarily produced?
    Відповідь
    (A)
    Cells responsible for sperm production
  • 30
    Which protein primarily carries testosterone through the bloodstream?
    Відповідь
    (C)
    A protein that binds to the male and female sex hormones
  • 31
    What are the breakdown products of androgens?
    Відповідь
    (B)
    17-Ketosteroids
  • 32
    Which androgen exhibits greater potency compared to testosterone?
    Відповідь
    (B)
    Dihydrotestosterone
  • 33
    Which hormone stimulates the release of androgens?
    Відповідь
    (A)
    LH
  • 34
    In the later stages of pregnancy, where does the majority of progesterone originate?
    Відповідь
    (B)
    Placenta
  • 35
    How is progesterone primarily carried within the bloodstream?
    Відповідь
    (A)
    Transcortin
  • 36
    What is the primary substance produced when progesterone is metabolized?
    Відповідь
    (B)
    Pregnanediol
  • 37
    Regarding progesterone secretion, which statement is accurate?
    Відповідь
    (B)
    Is more in second half of menstrual cycle than in first half
  • 38
    After menopause, women are at an increased risk of osteoporosis due to reduced levels of which hormone?
    Відповідь
    (C)
    Secretion of estrogen
  • 39
    Which hormone is utilized to confirm a pregnancy?
    Відповідь
    (D)
    Chorionic gonadotropin
  • 40
    The placenta produces all of the following hormones except:
    Відповідь
    (A)
    FSH
  • 41
    What is the number of amino acids that make up gastrin?
    Відповідь
    (C)
    Seventeen
  • 42
    In which part of the gastrin molecule is its biological activity found?
    Відповідь
    (B)
    C-terminal four amino acids
  • 43
    Which of the following is NOT true regarding β-endorphin?
    Відповідь
    (D)
    Its effects are not blocked by morphine
  • 44
    Which statement about epidermal growth factor is false?
    Відповідь
    (B)
    It has a quaternary structure
  • 45
    Met-enkephalin is best described as which of the following?
    Відповідь
    (B)
    A pentapeptide
  • 46
    Which substance is responsible for the vasoconstrictor effect of ADH?
    Відповідь
    (C)
    Protein kinase C
  • 47
    What enzyme controls the speed of catecholamine synthesis?
    Відповідь
    (B)
    Tyrosine hydroxylase
  • 48
    What substance can inhibit Dopa decarboxylase?
    Відповідь
    (C)
    α-Methyldopa
  • 49
    What inhibits the function of Tyrosine hydroxylase?
    Відповідь
    (A)
    Catecholamines
  • 50
    In which of the following conditions is the urinary excretion of vanillyl madelic acid elevated?
    Відповідь
    (A)
    Phaeochromocytoma