Quick Biochemistry - Hormone Metabolism (Section 3)

  • 1
    What is the typical range for serum insulin concentration?
    Sagot
    (A)
    4-25 μU/ml
  • 2
    A diabetic woman, after an overnight fast and a cup of black coffee, feels queasy and skips breakfast but still takes her insulin. What is the most likely outcome?
    Sagot
    (B)
    Hypoglycemia
  • 3
    What is a common consequence of insufficient insulin?
    Sagot
    (D)
    Presence of glucose in urine
  • 4
    What factor is the main trigger for the release of insulin?
    Sagot
    (C)
    Blood level of glucose
  • 5
    Which cells within the pancreatic islets are responsible for producing glucagon?
    Sagot
    (B)
    Glucagon
  • 6
    How many amino acids are present in a single glucagon polypeptide chain?
    Sagot
    (B)
    29
  • 7
    What is an approximate duration for the half-life of glucagon?
    Sagot
    (A)
    ~5
  • 8
    Which process is accelerated by the action of glucagon?
    Sagot
    (A)
    Hepatic glycogenolysis
  • 9
    What is the typical serum glucagon level during a fasting state?
    Sagot
    (B)
    20-100 pg/ml
  • 10
    Glucagon primarily functions to:
    Sagot
    (C)
    Increases gluconeogenesis in liver
  • 11
    In adult males, what is the typical range for serum free testosterone levels?
    Sagot
    (C)
    10-30 ng/dl
  • 12
    In adult females, what is the typical range for serum free testosterone levels?
    Sagot
    (B)
    0.3-2 ng/dl
  • 13
    Before puberty, what is the usual level of total serum testosterone?
    Sagot
    (A)
    <100 ng/100 ml
  • 14
    What is the typical range for total serum testosterone in adult men?
    Sagot
    (C)
    300-1000 ng/100 ml
  • 15
    What is the typical range for total serum testosterone in adult women?
    Sagot
    (C)
    20-80 ng/100 ml
  • 16
    What is the approximate range for serum estradiol in men?
    Sagot
    (C)
    24-68 pg/ml
  • 17
    During the first 10 days of a woman's menstrual cycle, what is the expected range for serum estradiol levels?
    Sagot
    (C)
    24-68 pg/ml
  • 18
    What is the typical range for serum estradiol levels in women during days 11-20 of their menstrual cycle?
    Sagot
    (B)
    50-300 pg/ml
  • 19
    What is the typical range for serum estradiol levels in women during days 21-30 of their menstrual cycle?
    Sagot
    (C)
    73-149 pg/ml
  • 20
    What is the approximate serum progesterone level during the follicular phase?
    Sagot
    (A)
    0.2-1.5 ng/100 ml
  • 21
    During a pregnancy, what is a typical serum progesterone concentration?
    Sagot
    (D)
    Greater than 24 ng/ml
  • 22
    In the luteal phase of the menstrual cycle, what serum progesterone levels are usually observed?
    Sagot
    (C)
    6.0-30 ng/ml
  • 23
    Which cells in the testes are responsible for the production of androgens?
    Sagot
    (B)
    Leydig cells
  • 24
    What hormone primarily regulates the activity of Leydig cells?
    Sagot
    (A)
    Intestitial cell stimulating hormone
  • 25
    What is the primary hormonal imbalance associated with Stein-Leventhal syndrome (Polycystic Ovary Syndrome)?
    Sagot
    (B)
    Androgens
  • 26
    What hormone is primarily responsible for stimulating progesterone production in the corpus luteum?
    Sagot
    (A)
    LH
  • 27
    In the process of testosterone synthesis, what is the crucial, rate-limiting step involving the conversion of a precursor?
    Sagot
    (A)
    Cholesterol to pregnenolone
  • 28
    What type of enzyme facilitates the conversion of androstenedione into testosterone?
    Sagot
    (B)
    Dehydrogenase
  • 29
    What enzyme is essential for the conversion of testosterone into estradiol?
    Sagot
    (A)
    Aromatase
  • 30
    What is the starting compound from which testosterone is synthesized?
    Sagot
    (D)
    Pregnenolone
  • 31
    In the context of urine analysis, what do urinary 17 ketosteroids primarily indicate?
    Sagot
    (B)
    Reflect the overall creation of androgen-related compounds
  • 32
    Which hormone is typically assessed in urine to determine pregnancy?
    Sagot
    (D)
    A hormone produced by the placenta
  • 33
    What is the approximate number of amino acids in human chorionic gonadotropin?
    Sagot
    (D)
    237
  • 34
    Which hormone, produced by the corpus luteum and placenta, is associated with relaxing pelvic tissues?
    Sagot
    (C)
    Relaxin
  • 35
    What is a synthetic progesterone frequently used in oral contraceptives?
    Sagot
    (A)
    Norethindrone
  • 36
    Why are young women often less susceptible to myocardial infarctions?
    Sagot
    (A)
    Estrogen
  • 37
    Hormone receptors exhibit all the following traits EXCEPT:
    Sagot
    (D)
    The quantity of receptors in a target cell is fixed
  • 38
    Which statement about hormone receptors is the most accurate?
    Sagot
    (D)
    Receptors can be reduced or increased in number based on conditions
  • 39
    What is the process of down-regulation?
    Sagot
    (D)
    A reduction in the number of receptors for a particular hormone
  • 40
    Which of the following statements about hormones is NOT generally true?
    Sagot
    (A)
    All hormones require specific transport proteins in the blood
  • 41
    Which of the following is NOT a characteristic of steroid hormones?
    Sagot
    (D)
    They utilize cyclic AMP as a secondary messenger
  • 42
    Which of the following hormones uses cyclic AMP as a secondary messenger?
    Sagot
    (D)
    All of these
  • 43
    Which of the following hormones does NOT use cyclic AMP as a secondary messenger?
    Sagot
    (A)
    Oxytocin
  • 44
    Which of the following utilizes cyclic GMP as a secondary messenger?
    Sagot
    (B)
    Atrial natriuretic factor
  • 45
    Certain hormones initiate intracellular effects by stimulating
    Sagot
    (C)
    Phospholipase C
  • 46
    What is the secondary messenger for the hormone(s) listed?
    Sagot
    (D)
    All of these
  • 47
    What role do G-proteins play?
    Sagot
    (D)
    Signal conversion
  • 48
    What component serves as the signal converter for glucagon?
    Sagot
    (C)
    Stimulatory G-protein
  • 49
    How are G-proteins structured?
    Sagot
    (C)
    Trimers
  • 50
    G-proteins interact with which type of nucleotide?
    Sagot
    (B)
    GDP/GTP