Quick Biochemistry - Nucleic Acids (Section 1)

  • 1
    What components combine to form a nucleoside?
    คำตอบ
    (B)
    A purine or pyrimidine base and a sugar
  • 2
    Which of the following best describes the composition of a nucleotide?
    คำตอบ
    (B)
    A purine and pyrimidine base, a sugar, and phosphorous
  • 3
    Which of the following is classified as a purine nucleotide?
    คำตอบ
    (A)
    AMP
  • 4
    Which option represents a pyrimidine nucleotide?
    คำตอบ
    (C)
    CMP
  • 5
    Adenine is also known as:
    คำตอบ
    (A)
    6-Amino purine
  • 6
    What is the other name for 2, 4-Dioxypyrimidine?
    คำตอบ
    (C)
    Uracil
  • 7
    What is the chemical designation for guanine?
    คำตอบ
    (B)
    2-Amino-6-oxypurine
  • 8
    In what units are the concentrations of nucleotides and nucleic acids frequently expressed?
    คำตอบ
    (D)
    OD at 260 nm
  • 9
    Which pyrimidine nucleotide is involved in high-energy intermediate reactions?
    คำตอบ
    (C)
    UDPG
  • 10
    In a nucleotide, what carbon position on the pentose molecule is involved in an ester bond with phosphate?
    คำตอบ
    (D)
    C₅
  • 11
    What molecule results from the combination of uracil and ribose?
    คำตอบ
    (A)
    Uridine
  • 12
    Which nucleotide is most prevalent in a free state within animal cells?
    คำตอบ
    (A)
    ATP
  • 13
    Approximately what is the average intracellular concentration of ATP in a mammalian cell?
    คำตอบ
    (A)
    1 mM
  • 14
    Which base is present in messenger RNA but absent in deoxyribonucleic acid?
    คำตอบ
    (D)
    Uracil
  • 15
    What is the function of 'Caps' in an RNA molecule?
    คำตอบ
    (B)
    Are unique to eukaryotic mRNA
  • 16
    How does prokaryotic mRNA differ from eukaryotic mRNA?
    คำตอบ
    (A)
    Can be polycistronic
  • 17
    What is the approximate size range of small stable RNA molecules?
    คำตอบ
    (C)
    90-300 nucleotides
  • 18
    What is the approximate range of small stable RNAs found within a single cell?
    คำตอบ
    (C)
    1,00,000-10,00,000
  • 19
    What is the approximate molecular weight of heterogenous nuclear RNA (hnRNA)?
    คำตอบ
    (A)
    More than 107
  • 20
    In RNA, why isn't the guanine content always equal to cytosine, and adenine always equal to uracil?
    คำตอบ
    (A)
    Single strand molecule
  • 21
    Which nitrogenous base is found in RNA?
    คำตอบ
    (B)
    Uracil
  • 22
    Which of the following is NOT a component of RNA?
    คำตอบ
    (C)
    Thymine
  • 23
    What type of sugar is found in RNA?
    คำตอบ
    (C)
    Ribose
  • 24
    Which statement accurately describes base pairing in an RNA molecule?
    คำตอบ
    (D)
    Guanine content does not necessarily equal its cytosine content.
  • 25
    In which type of RNA are methylated purines and pyrimidines typically found?
    คำตอบ
    (C)
    tRNA
  • 26
    Where is Thymine typically found?
    คำตอบ
    (A)
    tRNA
  • 27
    What is the approximate number of nucleotides in a tRNA molecule?
    คำตอบ
    (C)
    75
  • 28
    In a typical cell, what is the minimum number of different tRNA molecules present?
    คำตอบ
    (B)
    20
  • 29
    What shape does a tRNA molecule resemble?
    คำตอบ
    (C)
    Clover leaf
  • 30
    In tRNA molecules, the CCA sequence is always located at the:
    คำตอบ
    (A)
    3' Termini
  • 31
    What is the basis for classifying Transfer RNAs?
    คำตอบ
    (D)
    Extra arm
  • 32
    Which modified base is found in the D arm of a tRNA molecule, giving it its name?
    คำตอบ
    (A)
    Uridine
  • 33
    How many base pairs are typically found in the acceptor arm of a tRNA molecule?
    คำตอบ
    (B)
    7 Base pairs
  • 34
    How many base pairs does the anticodon arm of a tRNA molecule typically possess?
    คำตอบ
    (A)
    5 Base pairs
  • 35
    What sequence is typically found in the TΨC arm of a tRNA molecule?
    คำตอบ
    (A)
    T, pseudouridine and C
  • 36
    Who put forth the double helical structure model of DNA?
    คำตอบ
    (C)
    Watson and Crick
  • 37
    Which of the following is NOT found in DNA?
    คำตอบ
    (C)
    Uracil
  • 38
    What is the type of sugar molecule found in DNA?
    คำตอบ
    (A)
    Deoxyribose
  • 39
    DNA segments with a high concentration of A-T pairs are stabilized by how many hydrogen bonds?
    คำตอบ
    (B)
    2 Hydrogen bonds
  • 40
    Which statement accurately describes the base composition in a DNA molecule?
    คำตอบ
    (D)
    Guanine content equals cytosine content
  • 41
    DNA with a high proportion of G-C pairs tend to have what characteristic regarding hydrogen bonds?
    คำตอบ
    (C)
    3 Hydrogen bonds
  • 42
    Given that DNA carries an organism's genetic code, what can be logically inferred about its base composition across different tissues?
    คำตอบ
    (C)
    DNA from different tissues in the same organism should usually have the same base composition
  • 43
    What is the approximate width of the B-form DNA double helix in nanometers?
    คำตอบ
    (B)
    2
  • 44
    How many base pairs are typically found in a single complete turn of the B-form DNA molecule?
    คำตอบ
    (C)
    10
  • 45
    What is the distance, in nanometers, covered by one full turn of B-form DNA?
    คำตอบ
    (D)
    3.4 nm
  • 46
    If the thymine concentration in a DNA molecule is 30%, what is the predicted concentration of guanosine?
    คำตอบ
    (B)
    20%
  • 47
    If the guanosine content in a DNA molecule is 40%, what would be the percentage of adenine?
    คำตอบ
    (A)
    10%
  • 48
    What factor leads to a higher melting temperature in duplex DNA?
    คำตอบ
    (C)
    Cytosine + Guanine
  • 49
    What condition is often treated with the synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine?
    คำตอบ
    (B)
    Gout
  • 50
    Which synthetic nucleotide analogue is frequently used in cancer and viral infection treatment?
    คำตอบ
    (A)
    Arabinosyl cytosine