Essential Biochemistry - Connective Tissue (Section 1)
1
Which of the following is directly involved in the formation of a collagen fibril?
2
What is the main function of ground substance in connective tissue?
3
What disease is caused by a deficiency in ascorbic acid (vitamin C)?
4
What type of cross-links are present in elastin?
5
Which amino acids are frequently found in elastin?
6
Which of the following is a basic component of connective tissue?
7
Which of the following is found in large amounts in connective tissues that require elasticity?
8
Cross-links present in collagen are, except:
9
What is the role of Vitamin C in collagen synthesis?
Përgjigju(B)
A cofactor in hydroxylation reactions
10
Hydroxylation of proline requires which of the following?
11
What is the main difference between collagen and elastin regarding their ability to stretch?
Përgjigju(B)
Elastin can stretch and recoil, collagen cannot.
12
Which amino acid is crucial for the triple helix structure of collagen?
13
Which amino acid is crucial for the stabilization of the collagen helix?
14
A deficiency of copper affects the formation of normal collagen by reducing the activity of:
15
What type of collagen is found in basement membranes?
16
Which of the following is a characteristic of Ehlers-Danlos syndrome?
17
The basic subunit of elastic fibrils is:
18
What type of connective tissue is mainly affected in Marfan's syndrome?
19
In which condition is the dermis characterized by skin breaks and blistering?
20
Collagen contents of helix destabilizing amino acid is:
21
Which of the following components are found in the extracellular matrix of connective tissue?
22
Basic components of connective tissue are, except:
23
Which of the following is a characteristic of Marfan's Syndrome?
24
What is the role of lysyl oxidase in collagen formation?
25
What type of bond stabilizes the triple helix of collagen?
26
What is the role of proteoglycans in connective tissue?
27
Which of the following is NOT a type of cross-link in collagen?
28
Which of these is a symptom of Scurvy?
Përgjigju(B)
Easy bruising and bleeding
29
What is the function of elastin in connective tissue?
30
Which type of collagen is most abundant in skin?
31
What is the primary function of connective tissue?
Përgjigju(C)
Support, strength, and shape
32
Which of the following is a characteristic of osteogenesis imperfecta?
33
What is the primary function of glycoproteins in connective tissue?
34
What are the building blocks of tropocollagen?
35
Which of the following is not a genetic disorder of collagen?
36
Which of the following is NOT a characteristic of collagen?
Përgjigju(D)
Ability to stretch and recoil
37
What is the role of hydrogen bonds in the collagen structure?
Përgjigju(B)
They stabilize the collagen chains.
38
Which of the following is NOT a glycosaminoglycan (GAG)?
39
Which enzyme is inhibited in Lathyrism?
40
Which of the following is a dietary disorder related to connective tissue?
41
What is the primary function of glycoproteins in connective tissue?
42
What is the main difference between collagen and elastin?
Përgjigju(B)
Elastin has no repeating sequences while collagen does.
43
Which amino acids are crucial for the unique structure of collagen?
44
Cross-links present in collagen are, except:
45
What is a characteristic feature of Marfan's syndrome?
46
What is the primary function of collagen in connective tissue?
Përgjigju(B)
To provide tensile strength and support
47
Which of the following is NOT a type of collagen?
48
Which of the following are NOT usually found in the extracellular matrix of connective tissue?
49
Basic components of connective tissue are, except:
50
What is the consequence of the destruction of elastin by elastase?
