Essential Biochemistry - Muscle (Section 1)

  • 1
    The primary components of thin filaments include which of the following?
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    (C)
    Actin, tropomyosin and troponin
  • 2
    The following proteins are involved in muscle contraction, except:
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    (C)
    Myoglobin
  • 3
    Which of the following is true for sarcomere?
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    (D)
    All of the above
  • 4
    Which of the following does not change length during muscle contraction?
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    (C)
    A band
  • 5
    Which of the following acts as source of energy in muscle contraction?
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    A
    B
    C
  • 6
    Muscle tissue is responsible for:
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    (D)
    All of the above
  • 7
    The main function of the H-zone is to:
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    (C)
    contain myosin filaments
  • 8
    Which of the following acts in source of energy in muscle contraction?
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    A
    B
    C
  • 9
    The thick filament consists of the protein:
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    (C)
    Myosin
  • 10
    Which of the following is the main function of the H-zone?
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    (A)
    Contains the myosin filaments
  • 11
    What is the function of the M-line?
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    (B)
    Anchors thick filaments
  • 12
    The immediate source of energy for muscle contraction is:
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    (C)
    ATP
  • 13
    The contractile protein in muscle fiber is:
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    (C)
    Myosin
  • 14
    Which of the following is a function of the Z-lines?
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    (B)
    Anchoring the thin filaments
  • 15
    Which of the following is the correct sequence of events in the cross-bridge cycle?
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    (A)
    ATP binds, cross-bridge, power stroke, ADP release
  • 16
    The process by which muscle cells create the energy necessary for contraction is:
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    (D)
    All of the above
  • 17
    What molecule is directly responsible for the power stroke?
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    (C)
    Pi
  • 18
    Which of the following structures primarily contains actin?
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    (B)
    Thin filament
  • 19
    Which of the following describes the arrangement of myofilaments in striated muscle?
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    (A)
    Parallel
  • 20
    Which of the following is true for sarcomere?
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    (D)
    All of the above
  • 21
    The basic functional unit of a skeletal muscle is:
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    (A)
    Sarcomere
  • 22
    Which of the following describes the events occurring during muscle contraction?
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    (D)
    All of the above
  • 23
    Which event occurs FIRST in muscle contraction?
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    (B)
    Calcium binds to troponin
  • 24
    In the sliding filament theory of muscle contraction, what happens to the actin and myosin filaments?
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    (C)
    They slide past each other
  • 25
    Which protein is directly involved in blocking the myosin-binding sites on actin?
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    (C)
    Tropomyosin
  • 26
    In the resting state, the tropomyosin molecules lie:
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    (A)
    On top of the active sites of the actin strands
  • 27
    Which of the following statements best describes the role of the M-line in a sarcomere?
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    (B)
    It anchors the thick filaments
  • 28
    Which of the following is the main component of the thin filament?
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    (B)
    Actin
  • 29
    Actin is a polymer of globular-shaped subunit called:
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    (C)
    G-actin
  • 30
    The site where a motor neuron communicates with a muscle fiber is called:
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    (B)
    Neuromuscular junction
  • 31
    Which of these is the end product of the hydrolysis of ATP during muscle contraction?
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    (A)
    ADP + Pi
  • 32
    Which molecule directly covers the myosin-binding sites on actin, preventing the cross-bridge formation in a relaxed muscle?
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    (D)
    Tropomyosin
  • 33
    Where are the myosin heads located?
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    (B)
    Thick filaments
  • 34
    Which protein binds to calcium ions during muscle contraction?
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    (C)
    Troponin
  • 35
    What is the role of troponin?
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    (A)
    Regulating muscle contraction
  • 36
    The cells of skeletal muscle are cylindrical in shape and are commonly called:
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    (C)
    Muscle fibers
  • 37
    What is the name of the protein that makes up thick filaments?
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    (B)
    Myosin
  • 38
    Which structure is the functional unit of the muscle fiber?
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    (A)
    Sarcomere
  • 39
    Which of the following is the correct order of events during muscle contraction?
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    (D)
    ATP binds to myosin, release of ADP, cross-bridge formation, power stroke
  • 40
    Where does the energy for the power stroke come from?
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    (B)
    ATP hydrolysis
  • 41
    What is the primary fuel source used in muscle contraction?
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    (C)
    ATP
  • 42
    Which ion is essential for initiating muscle contraction?
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    (B)
    Calcium
  • 43
    What regulatory proteins are involved in muscle contraction?
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    (C)
    Tropomyosin & Troponin
  • 44
    During muscle contraction, which of the following bands/zones decreases in length?
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    (D)
    Both I band and H zone
  • 45
    The energy for muscle contraction is directly provided by:
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    (C)
    ATP
  • 46
    The central region of the A band is less dense than the rest of the band, and is called:
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    (C)
    H band
  • 47
    The primary components of thin filaments include which of the following?
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    (C)
    Actin, tropomyosin and troponin
  • 48
    What is the role of calcium ions in muscle contraction?
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    (C)
    To bind to troponin
  • 49
    Which of the following is the primary protein found in the thick filaments?
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    (B)
    Myosin
  • 50
    The thin filament consists of the protein:
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    (D)
    Both Actin and Tropomyosin