Quick Biochemistry - Proteins And Protein Metabolism (Section 10)
1
In the process of creating 1 molecule of urea within the Kreb's Hanseleit cycle, what is the count of ATP molecules that are utilized?
Answer
(C)
3
2
Which of the following are essential for the process of building proteins?
Answer
(D)
Amino acids, nucleic acids, ATP, GTP, enzymes and activators are required
3
What substance results from the transfer of a methyl group to guanidoacetic acid?
Answer
(A)
Creatine phosphate
4
Which two compounds, rich in energy, are essential for the process of protein synthesis?
Answer
(A)
ATP and GTP
5
Which ketoacid plays a role in the incorporation of dietary NH3 into an amino acid?
Answer
(B)
Oxalo acetate
6
Which of the following metabolites helps maintain the urea cycle?
Answer
(C)
Carbamoyl phosphate
7
To release tetra hydroglolate from N5 methyl tetrahydrofolate, what is needed?
Answer
(D)
Vitamin B12
8
The creation of a methyl group involves which of the following?
Answer
(C)
Interaction between N5 N10 methylene tetra hydrofolate with a NAD+ dependent reductase
9
Who or what group typically excretes a larger amount of creatinine?
Answer
(A)
Adult males
10
Why can a growing peptide within a ribosome not transfer to the next ribosome?
Answer
(C)
The gap between the ribosomes is too big for a shift
11
Which amino acid initiates polypeptide synthesis in a human ribosome?
Answer
(B)
Methionine
12
Which amino acid is the starting point for polypeptide synthesis in a bacterial ribosome?
Answer
(A)
N formyl methionine
13
Which molecule serves as a connection between the TCA cycle and the urea cycle?
Answer
(A)
Fumarate
14
A key characteristic of Bence Jones protein in urine is
Answer
(C)
Heat coagulability at 45 to 60°C
15
In which of the following conditions might Bence Jones proteins be found in a patient's urine?
Answer
(C)
Multiple myeloma
16
Which amino acid gives rise to xanthuric acid as an abnormal metabolite?
Answer
(D)
Tryptophan
17
In the urea cycle, where do the two nitrogen atoms of urea originate?
Answer
(B)
One from NH3 and one from aspartate
18
What molecule, when reacting with alanine in a transamination reaction, produces pyruvic acid?
Answer
(A)
α-keto glutaric acid
19
During the synthesis of one urea molecule in the Kreb's Henseleit cycle, how many AMP molecules are generated?
Answer
(A)
1
20
Which enzyme is crucial for the production of melanin from tyrosine?
Answer
(D)
Tyrosinase
21
In which of the following conditions is the quality of protein synthesis compromised?
Answer
(C)
Multiple myeloma
22
Citrulline is a key component of which biochemical process?
Answer
(B)
Urea cycle
23
Under the influence of what type of enzymes are semialdehydes produced?
Answer
(A)
Aldolases
24
Which of the following statements accurately describes a characteristic of a peptide bond?
Answer
(B)
It has cis hydrogen and oxygen groups
25
What is a characteristic of isoenzymes that catalyze a specific reaction?
Answer
(B)
Have identical affinities for the same substrate
26
Which protein is known for its high concentration of cystine?
Answer
(D)
Keratin
27
Following one cycle of Edman degradation on the peptide H2N—Gly—Arg—Lys—Phe— Asp— COOH, which of the provided structures (or their phenyl isothiocyanate derivatives) would be produced?
Answer
(C)
H₂N—Arg—lys—Phe—Asp—COOH + Gly
28
What method is employed to separate proteins based on their molecular weight differences?
Answer
(C)
SDS-gel Electrophoresis
29
Which amino acid, when abundant in a protein, would provide the greatest buffering capacity at a pH typically found within the body?
Answer
(B)
Histidine
30
Which amino acid is best suited to act as a buffer at a pH of 7?
Answer
(D)
Histidine
31
Regarding glutamine, which statement is accurate?
Answer
(C)
Includes an amide group
32
Which among the following is an amino acid?
Answer
(D)
Serine
33
In which amino acid does the lone pair of electrons on a ring nitrogen potentially act as a ligand, crucial for binding iron in hemoglobin?
Answer
(C)
Histidine
34
Which amino acid lacks optical activity?
Answer
(B)
Glycine
35
Optically active compounds demonstrate the ability to
Answer
(B)
Rotate the plane of polarized light
36
What serves as the reference compound for determining the absolute configuration of optically active compounds?
Answer
(C)
Glyceraldehyde
37
Excluding which pair, all standard amino acids contain one chiral carbon atom?
Answer
(B)
Isoleucine, Alanine
38
What is the primary function of complement proteins?
Answer
(B)
Supports the body's immunity
39
Optical isomers that are mirror images and cannot be superimposed are termed
Answer
(B)
Enantiomers
40
Why do living cells uniquely synthesize only one form of an optical isomer?
Answer
(B)
Due to 'l' form, stereospecific enzymes
41
At what pH does an amino acid exhibit a neutral charge?
Answer
(C)
Zero net charge
42
Which protein type shares characteristics with Albuminoids?
Answer
(C)
Both Albumin and Globulin
43
Which chain within a sickle cell's hemoglobin structure is altered?
Answer
(B)
Beta chain
44
What are the typical results for the protein flocculation test in a prehepatic jaundice scenario?
Answer
(A)
Normal or weakly positive
45
Which of the following amino acids lacks an aromatic ring in its side chain?
Answer
(B)
Alanine
46
What color change is observed when cysteine reacts in the Nitroprusside test?
Answer
(B)
Red
47
What type of bond links two cysteine residues together?
Answer
(A)
Disulfide
48
What is the name of the acid amide derived from Aspartic acid?
Answer
(C)
Asparagine
49
Which amino acid, crucial for certain enzyme active sites, possesses an ionizable side chain with a pK' close to 7?
Answer
(D)
Histidine
50
Which amino acid is highly prevalent in the composition of hemoglobin?
