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Quick Biochemistry - Nucleic Acids (Section 7)

1
What type of RNA is produced by RNA polymerase I in mammals?
Answer
(B)
rRNA
2
Which type of RNA is synthesized by RNA polymerase III in mammals?
Answer
(C)
tRNA
3
In mammals, which enzyme is responsible for creating mRNA?
Answer
(B)
RNA polymerase II
4
What molecule serves as the starting material for mRNA production?
Answer
(A)
mRNA
5
Which of the following is NOT a step in the modification of hnRNA after transcription?
Answer
(C)
Insertion of new nucleotides
6
Which of the following is NOT a change that happens to tRNA after it is first made?
Answer
(D)
Addition of a specific sequence at the end
7
In which of the following does post-transcriptional modification NOT take place?
Answer
(D)
Prokaryotic mRNA
8
The TATA box, a specific DNA sequence, is a binding site for what enzyme?
Answer
(B)
DNA-dependent RNA polymerase
9
Which of the following mRNA types does NOT have a polyadenylate tail?
Answer
(B)
Histone
10
In which of the following organisms are introns found in their DNA?
Answer
(C)
Man
11
Which of the following is a DNA polymerase found in mammals?
Answer
(A)
DNA polymerase a
12
Where in a mammalian cell is DNA polymerase γ typically found?
Answer
(C)
Mitochondria
13
In mammals, what enzyme primarily facilitates the duplication of genetic material within the cell's core?
Answer
(A)
DNA polymerase a
14
Which enzyme exhibits primase function?
Answer
(B)
DNA polymerase a
15
Which mammalian DNA polymerase plays a key role in rectifying mistakes during DNA replication?
Answer
(B)
DNA polymerase β
16
What cellular component's production is disrupted by Novobiocin?
Answer
(A)
DNA
17
The synthesis of which molecule is hindered by Ciprofloxacin?
Answer
(A)
DNA
18
What molecular target is inhibited by Ciprofloxacin?
Answer
(D)
DNA gyrase
19
Which cellular process is impaired by Rifampicin?
Answer
(D)
Initiation of transcription
20
To which molecule does Actinomycin D specifically attach?
Answer
(A)
Double stranded DNA
21
Certain DNA segments exhibit palindromic properties and
Answer
(C)
Are targeted by specific enzymes for cutting
22
Within genes, introns represent
Answer
(C)
Non-coding regions not translated into proteins
23
Which statement regarding tRNA processing is incorrect?
Answer
(C)
A specific cap is added to the 5' end
24
The impact of α-Amanitin primarily affects
Answer
(C)
RNA polymerase in eukaryotes
25
The function of Ciprofloxacin is to block the creation of
Answer
(A)
DNA in bacteria
26
Which is NOT a characteristic of bacterial promoters?
Answer
(D)
Contains a region with a high melting temperature
27
Which of the following statements about eukaryotic promoters is incorrect?
Answer
(A)
They can be positioned before or after the gene
28
In the method used to identify DNA sequences developed by Sanger, the replication process is halted by the introduction of
Answer
(B)
Another specific modified nucleotide
29
Where are the promoters for tRNA genes typically situated?
Answer
(C)
Within the gene
30
Regarding tRNA, which of the following statements is false?
Answer
(D)
The genes for rRNA occur in single copies
31
Where can you find anticodons?
Answer
(C)
+RNA
32
On which molecule can you locate codons?
Answer
(B)
hnRNA
33
Where are stop codons typically found?
Answer
(A)
mRNA
34
What is a characteristic of the genetic code that allows it to be called degenerate?
Answer
(D)
More than one codons can code for the same amino acids
35
Which statement about the genetic code is incorrect?
Answer
(D)
It is overlapping
36
Which statement about stop codons is false?
Answer
(C)
They are identical in nuclear and mitochondrial DNA
37
Which type of cell typically has polycistronic mRNA?
Answer
(A)
Prokaryotes
38
In which organisms would you typically find genes with non-coding sequences?
Answer
(C)
Eukaryotes
39
What term is used to describe the non-coding parts of a gene?
Answer
(C)
Introns
40
Where would you find splice sites?
Answer
(C)
Eukaryotic hnRNA
41
Which of the following is NOT a common characteristic of introns?
Answer
(C)
The terminal AG sequence is followed by a region rich in purines
42
A spliceosome includes all of the following components EXCEPT:
Answer
(D)
Ribosomes
43
Self-splicing can be observed in:
Answer
(A)
Some precursors of rRNA
44
Where is the Pribnow box located?
Answer
(A)
In promoters of prokaryotes
45
Where is the Hogness box found?
Answer
(B)
In promoters of eukaryotes
46
What is the typical location of the CAAT box relative to the transcription start site in eukaryotic promoters?
Answer
(D)
Eukaryotic promoters 70-80 bp upstream
47
Which of the following is/are present in eukaryotic promoters?
Answer
(C)
Both (A) and (B)
48
Which of the following statements about tRNA is NOT accurate?
Answer
(B)
The anticodon of tRNA recognizes the amino acid
49
Which of the following is INCORRECT regarding the charging of tRNA?
Answer
(B)
ATP is converted to ADP and inorganic phosphate during the process
50
Which of the following is NOT true regarding the recognition of a codon on mRNA by an anticodon on tRNA?
Answer
(D)
Wobble leads to incorporation of incorrect amino acids in the protein