Quick Biochemistry - Nucleic Acids (Section 4)
1
What is the name of the DNA sequence where a repressor binds to control transcription?
2
Which cellular process involves Okazaki fragments?
3
What is the function of the TATA BOX within a DNA sequence?
Answer(C)
DNA dependent RNA polymerase binding site
4
What type of molecule does reverse transcriptase create?
5
Which virus is classified as a retrovirus?
6
Where does peptidyl transferase activity take place?
7
What specific type of DNA damage can be caused by exposure to ultraviolet light?
Answer(B)
Two adjacent pyrimidine residues forming a dimer
8
Which enzyme is deficient in individuals with Hurler's syndrome?
9
Which chemical reaction is used to identify the presence of arginine?
10
Which base is typically absent in messenger RNA?
11
How are phosphate groups connected to sugar molecules in nucleotides?
12
From which molecule can cyclic AMP be synthesized?
13
Which modified pyrimidine base has pharmaceutical applications?
14
What was the identity of the 'transforming factor' identified by Avery, McLeod, and McCarty?
15
What is the base that pairs with adenine in DNA?
16
In a DNA molecule, which base pair forms three hydrogen bonds?
17
Which type of DNA exhibits a left-handed double helix structure?
18
What type of molecules associate with nuclear DNA?
Answer(C)
Both histones and non-histones
19
In which of the following is the number of guanine and cytosine molecules approximately equal?
20
Which of the following is resistant to hydrolysis by alkalis?
21
Where are codons typically found?
22
During the attachment process, where does an amino acid bind to transfer RNA?
23
In organisms without a nucleus, what are the components of ribosomes?
24
What is the nature of ribozymes?
25
Which type of RNA is the smallest in size?
26
In which of the following molecules are the quantities of adenine and thymine the same?
27
In a DNA molecule, how many hydrogen bonds connect adenine and thymine?
28
What base pairs with adenine in RNA?
29
Where would you find genetic material outside the cell nucleus?
30
Where is mitochondrial DNA found?
31
Which type of biological molecule contains Ribothymidine?
32
In which form of DNA does one helical turn consist of ten base pairs?
33
What is the primary function of transfer RNA?
Answer(C)
Amino acids from cytosol to ribosomes
34
Which condition is associated with a deficiency in ceramidase?
35
Ceramide is a component of all of the following EXCEPT:
36
From where can the building blocks for nucleic acid synthesis come?
Answer(D)
De novo synthesis and salvage
37
Where does the de novo synthesis of purine nucleotides take place?
38
Which molecules are sources of nitrogen atoms for the de novo synthesis of purine nucleotides?
Answer(C)
Aspartate, glutamine and glycine
39
How many atoms does glycine contribute to the de novo synthesis of purine nucleotides?
Answer(D)
One nitrogen and two carbon atoms
40
What position on a purine ring is supplied by aspartate during de novo synthesis?
41
Which molecule donates carbon 6 in the purine ring structure?
42
What is the role of 5-Phosphoribosyl-1-pyrophosphate in nucleotide synthesis?
Answer(C)
Both purine and pyrimidine nucleotides
43
During the de novo synthesis process, inosine monophophate acts as an intermediate for the creation of which nucleotide(s)?
44
During de novo synthesis, xanthosine monophosphate serves as an intermediate in the formation of which nucleotide?
45
Which of the following enzymes is NOT an allosteric enzyme in the de novo synthesis pathway of purine nucleotides?
46
Which enzyme is NOT exclusive to purine nucleotide synthesis?
47
What molecules inhibit PRPP synthetase through allosteric regulation?
48
Which molecule acts as an allosteric inhibitor for PRPP glutamyl amido transferase?
49
Which molecule allosterically inhibits adenylosuccinate synthetase?
50
Which molecule serves as an allosteric inhibitor of IMP dehydrogenase?
