Quick Biochemistry - Hormone Metabolism (Section 4)
1
The location of the nucleotide binding site on G-proteins is on their
2
Adenylate cyclase is stimulated by
Answer(B)
GTP-bound a-Subunit of G-protein
3
Which of the following receptors exhibits tyrosine kinase activity?
4
The insulin receptor exists as a
5
Which receptor demonstrates tyrosine kinase activity?
6
The activation of Protein kinase C is triggered by
7
Where is melatonin produced?
8
Melatonin is derived from
9
The secretion of Melanocyte stimulating hormone originates in the
Answer(D)
Intermediate lobe of pituitary gland
10
What effect does MSH have?
Answer(B)
Increase in melanin concentration in melanocytes
11
What mechanism governs the release of MSH?
Answer(C)
Hormones from the hypothalamus
12
Which hormone is produced within the hypothalamus?
13
What hormone is released by the rear pituitary gland?
14
Which of these choices represents a nonapeptide?
15
A shortage of which hormone leads to diabetes insipidus?
16
What substance, in high amounts, leads to blood vessel constriction in the body's periphery?
17
Where is somatotropin produced?
18
What substance promotes the release of Insulin-like Growth Factor-l?
20
The release of growth hormone is reduced by
21
Which substance stimulates the release of somatotrophin?
Answer(C)
Growth hormone releasing hormone
22
What is the structure of human growth hormone?
Answer(B)
One polypeptide chain and two intra-chain disulphide bond
23
How many amino acid residues are present in human growth hormone?
24
How many amino acid residues are present in prolactin?
25
The secretion of prolactin is controlled by which of the following?
Answer(C)
Prolactin release inhibiting hormone
26
Which molecule is the precursor of ACTH?
27
Which of the following is NOT a product of pro-opiomelanocortin?
28
Which statement about pro-opiomelanocortin is incorrect?
Answer(C)
It is the precursor of ACTH and melatonin
29
Which statement about ACTH is false?
Answer(D)
Its second messenger is inositol triphosphate
30
What mechanisms regulate ACTH secretion?
Answer(C)
CRH and feedback inhibition by cortisol
31
ACTH is composed of how many amino acids?
32
CRH is composed of how many amino acids?
33
The hormonal function of ACTH is completely lost if which of the following is removed?
34
Which statement regarding TSH is incorrect?
Answer(D)
Its subunit is identical with those of FSH and LH
35
Which of the following statements about TSH is false?
Answer(B)
It acts on para-follicular cells of thyroid glands
36
Which statement about thyrotropin releasing hormone is not true?
37
In males, where does luteinizing hormone have its effect?
38
Which of the following statements concerning FSH is not correct?
Answer(D)
It increases the synthesis of testosterone
39
In males, which of the following inhibits the release of luteinizing hormone?
Answer(C)
High blood level of testosterone
40
What factor stimulates the release of luteinizing hormone?
41
What hormone does HCG's structure and function most closely resemble?
42
What condition is a consequence of excessive production of a specific hormone in adulthood?
Answer(D)
Growth hormone during adult life
43
Which of the following is NOT a result of acromegaly?
44
Excessive growth hormone production during youth leads to which condition?
45
A reduced secretion of a certain hormone during childhood is associated with which condition?
46
Which condition is characterized by an increase in height?
47
Which amino acid serves as a precursor for thyroid hormone synthesis?
48
What enzyme is essential for the production of thyroid hormones?
49
Which substance does thyroperoxidase act upon to introduce iodine?
Answer(B)
Tyrosine residues of thyroglobulin
50
At which positions are tyrosine residues iodinated in the thyroxine molecule?
