Quick Biochemistry - Enzymes (Section 6)
1
What is the correct order of lipoprotein molecules, from least to most dense?
Answer(B)
Chylomicron, VLDL, IDL, LDL
2
What substance is present in the urine of individuals with Hurler's syndrome?
Answer(C)
Dermatan sulphate and heparan sulphate
3
Which enzyme is deficient in Hunter's syndrome?
4
Which of the following is a characteristic of Hunter's syndrome?
Answer(D)
Hearing loss is perceptive
5
What is a key characteristic of Von-Gierke's disease?
6
Which organ is primarily affected in McArdle's syndrome?
7
What enzyme is deficient in Refsum's disease?
8
What is a significant finding in Refsum's disease?
Answer(B)
Accumulation of phytanic acid in the blood and tissues
9
Which disease is associated with a deficiency in the a-Galactosidase enzyme?
10
Which model or theory explains the formation of an enzyme-substrate complex?
11
A key characteristic of Tay-Sachs disease involves
Answer(B)
Buildup of specific lipids in the brain and spleen
12
Which enzyme is missing in Krabbe's disease?
13
A deficiency in which enzyme causes Farber's disease?
14
Niemann-Pick disease results from the lack of which enzyme?
15
Wolman's disease is caused by the absence of
Answer(A)
Cholesteryl ester hydrolase
16
What enzyme is missing in Sandhoff's disease?
17
What enzyme is affected in Jamaican vomiting sickness?
18
What is the cause of Zellweger's syndrome?
19
What is the underlying issue in Bassen-Kornzweig syndrome?
Answer(B)
Defect in Apo-B synthesis
20
What enzyme deficiency is associated with Hyperammonemia type II?
Answer(C)
Ornithine transcarbamoylase
21
What is a notable observation in Hyperammonemia type II?
22
A lack of the argininosuccinate synthetase enzyme results in which condition?
Answer(A)
Argininosuccinic aciduria
23
What condition is characterized by Tricorrhexis nodosa?
24
Which condition is associated with high blood argininosuccinate levels?
25
Hyperargininemia, a urea synthesis impairment, arises from a deficiency of which enzyme?
26
The deficiency of which enzyme causes albinism?
Answer(C)
p-Hydroxyphenylpyruvic acid oxidase
27
What enzyme deficiency leads to neonatal tyrosinemia?
Answer(B)
Fumarylacetoacetate hydrolase
28
Which enzyme demonstrates substrate specificity?
30
In which type of reactions are coenzymes essential?
31
Which coenzyme plays a role in moving hydrogen atoms during chemical reactions?
32
Which coenzyme is involved in reactions that involve the gain or loss of electrons?
33
During the process of turning glucose into glucose-6-phosphate, what molecule acts as a helper?
34
What coenzyme is necessary for reactions that move amino groups between molecules?
35
Coenzyme A includes a specific type of vitamin. Which vitamin is it?
36
What vitamin is found within cobamides?
37
Which coenzyme is crucial for reactions where carbon dioxide is added to a molecule?
38
Which coenzyme is involved in the process of cells using oxygen to produce energy?
39
The enzyme hexokinase is classified as which type of enzyme based on its function?
40
Which of the following enzymes is responsible for breaking down proteins?
41
What type of enzymes facilitate the formation of covalent bonds between two substrates?
42
The scientist who put forward the induced fit model of enzyme function was
43
Another term for allosteric inhibition is
44
Typically, an allosteric enzyme's activity is reduced by
45
If an enzymatic reaction reaches its maximum velocity (Vmax), what is the substrate concentration relative to Km?
46
On a Lineweaver-Burk plot, the y-intercept signifies
47
In the context of competitive inhibition, the inhibitor
Answer(D)
Competes with the substrate
48
What is the effect of competitive inhibitors on the enzyme kinetics?
49
How can the effect of competitive inhibition be mitigated?
50
Which enzyme does physostigmine competitively inhibit?
