$$\begin{aligned} & \left|\begin{array}{ccc} 1+\sin ^2 x & \cos ^2 x & 4 \sin 4 x \\ \sin ^2 x & 1+\cos ^2 x & 4 \sin 4 x \\ \sin ^2 x & \cos ^2 x & 1+4 \sin 4 x \end{array}\right|, x \in R \\ & R_2 \rightarrow R_2-R_1 \& R_3 \rightarrow R_3-R_1 \\ & f(x)\left|\begin{array}{ccc} 1+\sin ^2 x & \cos ^2 x & 4 \sin 4 x \\ -1 & 1 & 0 \\ -1 & 0 & 1 \end{array}\right| \end{aligned}$$

Expand about $\mathrm{R}_1$, we get

$$f(x)=2+4 \sin 4 x$$

$\therefore M=\max$ value of $f(x)=6$

$\mathrm{m}=\mathrm{min}$ value of $\mathrm{f}(\mathrm{x})=-2$

$$\therefore \mathrm{M}^4-\mathrm{m}^4=1280$$