JAMB - Biology (2025 - No. 62)
Explanation
Agglutination is the clumping of red blood cells (erythrocytes) that occurs when incompatible blood types are mixed during a transfusion. The recipient's pre-existing antibodies recognize the foreign antigens on the donor's red blood cells and bind to them, causing them to stick together and form clumps.
B. donor and recepient belong to different races: Race does not determine blood compatibility; genetic factors determine blood type. Cross-racial transfusions are safe if the blood types are compatible.
C. same antibodies from donor and recipient fuse together: Agglutination is an antigen-antibody reaction, not the fusion of antibodies. It involves the binding of antibodies to specific antigens.
D. donor and the recipient belong to the same blood group: Agglutination does not occur when the donor and recipient belong to the same, compatible blood group because there are no incompatible antigens and antibodies to react with each other.
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