A deficiency in vitamin E can lead to hemolytic anemia and neurological deficits.

Night blindness can be caused by a deficiency in vitamin A. Vitamin A is essential for the production of pigments in the retina that help you see in low light. 

Vitamin K is essential for the production of proteins that help the blood clot, and a deficiency leads to impaired coagulation.

A major disease caused by severe vitamin C deficiency is scurvy. Scurvy is a disease caused by a severe and prolonged deficiency of vitamin C, leading to symptoms like fatigue, bleeding gums, skin hemorrhages, and impaired wound healing.