JAMB - Biology (2003 - No. 38)

A man and his wife are both heterozyous for the sickle-cell trait. The likely percentage of their offspring that will be either carriers or sicklers is
75%
50%
25%
100%

Explanation

An heterozygote for sickle-cell anaemia = AS

Crossing two AS persons, we have one AA, two AS and one SS.

\(\therefore\) The probability that the children are either carriers or sicklers = \(\frac{3}{4}\)

= 75%

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