Essential Biochemistry - Vitamins (Section 3 - No. 40)
What reaction does the enzyme thymidylate synthase catalyze?
Conversion of deoxyuridylate (dUMP) to thymidylate (dTMP)
Conversion of deoxycytidylate (dCMP) to thymidylate (dTMP)
Conversion of deoxyuridylate (dUMP) to deoxycytidylate (dCMP)
Conversion of deoxycytidylate (dCMP) to deoxyuridylate (dUMP)
Explanation
The enzyme thymidylate synthase (thymidylate synthetase) that converts deoxyuridylate (dUMP) to thymidylate (dTMP) uses N5, N10-methylene THF as the methyl donor for this reaction.
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