Essential Biochemistry - Regulation Of Gene Expression And Mutation (Section 2 - No. 11)
Which of the following mutations would likely have the least severe impact on a protein?
Deletion of one nucleotide.
Insertion of one nucleotide.
Insertion of three nucleotides.
Substitution of one nucleotide leading to a change in amino acid.
Explanation
A frameshift due to the insertion of three nucleotides, because it adds an entire codon with little change
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