Essential Biochemistry - Protein Metabolism (Section 9 - No. 27)
Which enzyme catalyzes the first committed step of the urea cycle?
Arginase
Carbamoyl phosphate synthetase I
Ornithine transcarbamylase
Aspartate transaminase
Explanation
Carbamoyl phosphate synthetase I catalyzes the synthesis of carbamoyl phosphate from ammonia, carbon dioxide, and ATP, which is the committed step of the urea cycle.
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