Essential Biochemistry - Protein Metabolism (Section 9 - No. 27)

Which enzyme catalyzes the first committed step of the urea cycle?
Arginase
Carbamoyl phosphate synthetase I
Ornithine transcarbamylase
Aspartate transaminase

Explanation

Carbamoyl phosphate synthetase I catalyzes the synthesis of carbamoyl phosphate from ammonia, carbon dioxide, and ATP, which is the committed step of the urea cycle.

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