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Essential Biochemistry - Plasma Proteins And Immunoglobulins (Section 2)

1
Albumin is exclusively synthesized by
Answer
(A)
Liver
2
In which condition does serum albumin decrease?
Answer
A
B
C
3
Bence Jones proteins are:
Answer
(A)
Monoclonal heavy chains
4
What are the major classes of plasma proteins?
Answer
(D)
All of the above
5
Which immunoglobulin is found in external secretions?
Answer
(A)
IgA
6
Serum protein electrophoretic patterns provide useful diagnostic information
Answer
(A)
True
7
Which immunoglobulin is primarily involved in the defense against helminths (parasitic worms)?
Answer
(D)
IgE
8
What is a characteristic of Bence Jones proteins?
Answer
(B)
Monoclonal light chains
9
Where is the remainder of the globulins formed?
Answer
(B)
Lymphoid tissue
10
In what condition does the level of α1-antitrypsin (AAT) decrease?
Answer
(A)
Emphysema
11
Which condition can lead to increased levels of IgG and elevated γ-globulin in the serum?
Answer
(B)
Multiple myeloma
12
What is the function of transferrin?
Answer
(B)
Transport of iron
13
Light present on the surface of B lymphocyte is:
Answer
(A)
Monomer
14
Which is responsible for neutralizing bacterial toxins and binds to microorganisms?
Answer
(A)
IgG
15
Which is an example of an essential amino acid?
Answer
(D)
All of the above
16
What is the primary function of antibodies?
Answer
(B)
To defend against infectious agents
17
Which protein, when deficient, can lead to emphysema?
Answer
(B)
α₁-antitrypsin
18
What is the function of α1-antitrypsin?
Answer
(A)
Inhibits protease activity
19
Hypoalbuminemia may be due to:
Answer
(D)
All of the above
20
Which class of immunoglobulins is the major antibody in secretions such as saliva, tears, and intestinal and genital tract secretions?
Answer
(C)
IgA
21
Which immunoglobulin is involved in allergic reactions?
Answer
(A)
IgE
22
Where are the α and β globulins synthesized?
Answer
(A)
Liver
23
Which of the following antibody is responsible for anaphylactic type of hypersensitivity and allergy?
Answer
(D)
IgE
24
What is the main function of fibrinogen?
Answer
(B)
Blood clotting
25
Cigarette smoke inhibits the activity of:
Answer
(A)
α₁-antitrypsin
26
What is the function of haptoglobin?
Answer
(C)
Bind free hemoglobin
27
Which plasma protein is responsible for the maintenance of blood viscosity?
Answer
(B)
Fibrinogen
28
What is the most abundant immunoglobulin class in serum?
Answer
(A)
IgG
29
Which is the first antibody produced by B cell upon infection?
Answer
(C)
IgM
30
Following are pentameric immunoglobulins:
Answer
(C)
IgM