Essential Biochemistry - Nucleic Acid Metabolism (Section 4 - No. 10)
What is the role of dihydrofolate reductase in nucleotide metabolism?
It provides the substrate for thymidylate synthase.
It reduces dihydrofolate to tetrahydrofolate
It converts UMP to CTP
It is involved in purine degradation.
Explanation
Dihydrofolate reductase reduces dihydrofolate to tetrahydrofolate, which is needed for thymidine synthesis.
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