Essential Biochemistry - Nucleic Acid Metabolism (Section 3 - No. 28)
The synthesis of purine nucleotides is controlled by:
Concentration of PRPP
Feedback regulation of several steps
Increased concentrations of PRPP stimulate the purine nucleotide synthesis.
Availability of almond phosphate
Explanation
Purine nucleotide synthesis is regulated by the concentration of PRPP, feedback regulation, and the concentration of PRPP.
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