Essential Biochemistry - Nucleic Acid Metabolism (Section 3 - No. 25)
What is the first step in pyrimidine biosynthesis?
Formation of carbamoyl phosphate
Attachment of ribose-5-phosphate
Formation of orotic acid
Conversion of UMP to CTP
Explanation
The first step is the formation of carbamoyl phosphate by carbamoyl phosphate synthetase II (CPSII).
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