Essential Biochemistry - Nucleic Acid Metabolism (Section 3 - No. 10)
Which enzyme catalyzes the committed step in the synthesis of pyrimidine nucleotides?
Carbamoyl phosphate synthetase II
Aspartate transcarbamoylase
Dihydroorotase
Orotate phosphoribosyltransferase
Explanation
Carbamoyl phosphate synthetase II catalyzes the committed step.
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