Essential Biochemistry - Nucleic Acid Metabolism (Section 2 - No. 1)
In the synthesis of pyrimidine nucleotides, what is the role of dihydroorotate dehydrogenase?
Catalyzes the formation of orotate from dihydroorotate.
Adds a phosphate group to UMP
Adds an amino group to cytosine.
Converts GMP to UMP
Explanation
Dihydroorotate dehydrogenase converts dihydroorotate to orotate.
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