Essential Biochemistry - Nucleic Acid Metabolism (Section 1 - No. 35)
Which of the following statements best describes the role of feedback inhibition in purine synthesis?
Excess of purine nucleotides stimulate the pathway.
Purine nucleotides inhibit the enzyme, PRPP amidotransferase.
The pathway doesn't have any feedback regulation.
Pyrimidine nucleotides are the main regulators of purine synthesis
Explanation
Purine nucleotides inhibit PRPP amidotransferase.
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