Essential Biochemistry - Nucleic Acid Metabolism (Section 1 - No. 30)
Which enzyme is directly inhibited by IMP, AMP, and GMP in purine synthesis?
PRPP synthetase
PRPP amidotransferase
Adenylosuccinate synthetase
Inosinate dehydrogenase
Explanation
PRPP amidotransferase is the enzyme directly inhibited by IMP, AMP, and GMP.
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