Essential Biochemistry - Nucleic Acid Metabolism (Section 1 - No. 23)
Which of the following is a characteristic of SCID due to ADA deficiency?
Accumulation of deoxyadenosine and dATP in the lymphocytes.
Normal T-cell function.
Elevated levels of uric acid.
Increased resistance to infections.
Explanation
ADA deficiency leads to accumulation of deoxyadenosine and dATP in lymphocytes.
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