Essential Biochemistry - Nucleic Acid Metabolism (Section 1 - No. 22)
What enzyme is directly inhibited by IMP, AMP, and GMP in purine synthesis?
PRPP synthetase
PRPP amidotransferase
Adenylosuccinate synthetase
Inosinate dehydrogenase
Explanation
PRPP amidotransferase is directly inhibited by these purine nucleotides.
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