Essential Biochemistry - Nucleic Acid Metabolism (Section 1 - No. 12)
Which enzyme is directly responsible for the de novo synthesis of purines?
Adenine phosphoribosyltransferase
Hypoxanthine-guanine phosphoribosyltransferase
PRPP amidotransferase
Xanthine oxidase
Explanation
PRPP amidotransferase is directly responsible for the de novo synthesis of purines.
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