Essential Biochemistry - Lipid Metabolism (Section 8 - No. 7)

Which enzyme catalyzes the first committed step in fatty acid synthesis?
Acyl-CoA dehydrogenase
Acetyl-CoA carboxylase
Fatty acid synthase
Carnitine acyltransferase I

Explanation

Acetyl-CoA carboxylase converts acetyl-CoA to malonyl-CoA, which commits the pathway to fatty acid synthesis.

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