Essential Biochemistry - Lipid Metabolism (Section 2 - No. 5)
Rate controlling step of cholesterol biosynthesis is:
Squalene -> Lanosterol
HMG-CoA -> Mevalonic acid -> CoA
Acetyl-CoA + Acetoacetyl-CoA -> HMG-CoA
Lanosterol -> Cholesterol
Explanation
HMG-CoA reductase is the rate limiting step.
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