Essential Biochemistry - Lipid Metabolism (Section 13 - No. 34)
Which enzyme catalyzes the first committed step in fatty acid synthesis?
Fatty acid synthase
Acetyl-CoA carboxylase
Citrate synthase
Malonyl-CoA transferase
Explanation
Acetyl-CoA carboxylase catalyzes the rate-limiting step, which is the carboxylation of acetyl-CoA to malonyl-CoA.
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