Essential Biochemistry - Hemoglobin Metabolism (Section 2 - No. 49)

The first step in the biosynthesis of porphyrins is the condensation of:
glycine and succinyl CoA to form 5-aminolevulinic acid.
glycine and acetyl CoA to form 5-aminolevulinic acid.
glutamate and succinyl CoA to form 5-aminolevulinic acid.
glutamate and acetyl CoA to form 5-aminolevulinic acid.

Explanation

The first step in the biosynthesis of porphyrins is the condensation of glycine and succinyl CoA to form 5-aminolevulinic acid.

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