Essential Biochemistry - Enzymes (Section 5)
1
In feedback allosteric inhibition, the first enzyme of the sequence is inhibited by:
Answer(B)
The end product of the multienzyme system
2
Dilsulfiram is used to treat:
3
What is a key feature of how irreversible inhibitors interact with enzymes?
Answer(B)
They often form covalent bonds.
4
Which enzyme class is involved in the transfer of a group from one molecule to another?
5
Which of the following is NOT an example of a noncompetitive inhibitor?
6
In the process of feedback inhibition, the inhibited enzyme is most frequently:
Answer(C)
The first enzyme in the pathway.
7
Asparin inactivates the enzyme:
8
Which enzyme does DFP inhibit?
9
Asparaginase is used to treat which condition?
10
DDT, an insecticide, is an example of a:
Answer(C)
Group-specific irreversible inhibitor.
11
Which of the following is a characteristic of reversible inhibitors?
12
What is the primary function of DFP as an inhibitor?
Answer(A)
To inhibit Acetylcholinesterase
13
The target enzyme of aspirin is:
14
DDT can be classified as which type of inhibitor?
Answer(C)
Group-specific irreversible inhibitor
15
Aspirin inactivates which enzyme?
16
What type of inhibition is seen when the inhibitor has a structure similar to the substrate?
17
Liver diagnostic enzyme is:
18
Dilsulfiram is used in the treatment of:
19
What is the role of cofactors in enzyme reactions?
Answer(B)
They directly participate in catalysis
20
Aspirin's main target is:
21
Dilsulfiram is a drug used to treat alcoholism because it inhibits:
22
What type of reaction is catalyzed by a hydrolase?
23
The binding site of an allosteric regulator is:
24
The enzyme useful in the treatment of leukemia is:
25
The primary mode of action for noncompetitive inhibitors involves:
Answer(C)
Binding to a site other than the active site, affecting Vmax.
26
Ethanol and certain anorexic drugs are examples of which type of inhibitor?
27
Enzymes are used in which of the following?
28
Group specific irreversible inhibitors target:
Answer(A)
Specific functional groups
29
Aspirin inhibits which enzyme?
30
An elevated CK-MB level indicates:
31
Which of the following are used in the treatment of leukemia?
32
What happens to Km in the presence of a competitive inhibitor?
33
In enzyme kinetics, Vmax represents:
Answer(B)
The maximum rate of an enzymatic reaction
34
Feedback inhibition regulates which component of the pathway?
Answer(B)
The first enzyme in the pathway
35
How do enzymes affect the equilibrium constant (Keq) of a reaction?
36
Noncompetitive inhibitors primarily impact enzyme function by:
Answer(C)
Binding elsewhere on the enzyme, changing Vmax.
37
In obstructive jaundice, which of the following enzyme levels typically increase?
38
Enzymes may be used as the following, except:
39
The analysis of certain plasma enzymes is primarily used for:
40
Which of the following is used to treat leukemia?
41
Enzymes are biological catalysts that:
Answer(A)
Increase the rate of chemical reactions
42
The active site of an enzyme is the region that:
Answer(C)
Both binds and catalyzes the reaction
43
Which of the following is NOT a characteristic of enzymes?
Answer(B)
Require activation energy
44
Which of the following is an example of a physiological agent influencing enzyme activity?
45
The LDH1 tetramer is made of which polypeptide types?
46
Enzymes are utilized for:
47
The allosteric effect involves binding at which site on the enzyme?
48
Dilsulfiram is used in the treatment of which condition?
49
The effect of dilsulfiram on aldehyde dehydrogenase leads to:
Answer(B)
Accumulation of acetaldehyde.
50
An enzyme can be used for:
