Essential Biochemistry - Enzymes (Section 3 - No. 6)
What effect does a competitive inhibitor have on Km and Vmax?
Km increases, Vmax decreases
Km decreases, Vmax increases
Km increases, Vmax stays the same
Km decreases, Vmax stays the same
Explanation
Competitive inhibitors increase Km (because more substrate is needed to reach the same reaction rate) but do not affect Vmax (as the substrate can still eventually overcome the inhibitor if enough is added).
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