Essential Biochemistry - Detoxification (metabolism Of Xenobiotics) (Section 3 - No. 6)
The primary purpose of biotransformation is to:
Convert lipophilic compounds to more polar compounds
Convert polar compounds to more lipophilic compounds
Increase toxicity
Decrease water solubility
Explanation
The primary purpose of the biotransformation process is to convert the lipophilic, nonpolar, toxic compound to more polar, water soluble forms to decrease the permeability of the toxic compound.
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