Essential Biochemistry - Detoxification (metabolism Of Xenobiotics) (Section 2 - No. 31)
What is the general reaction of conjugation with Glucuronic acid?
XOH + UDP-Glucuronate -> X-Glucuronate + UDP
Bilirubin + 2 UDP-Glucuronate -> Bilirubin diglucuronide + UDP
Acetyl-CoA + X -> Acetyl-X + CoA
PAPS + XOH -> XO-SO3- + PAP
Explanation
The general reaction involves addition of UDP-Glucuronate and bilirubin.
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