Essential Biochemistry - Chemistry Of Proteins (Section 4 - No. 14)

Which of the following statements is true regarding the role of proline in protein structure?
Proline disrupts alpha-helices.
Proline stabilizes beta-sheets.
Proline is a polar amino acid.
Proline is a basic amino acid.

Explanation

Proline's unique cyclic structure introduces a kink in the polypeptide chain and disrupts the formation of alpha-helices.

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