Essential Biochemistry - Chemistry Of Hemoglobin (Section 2 - No. 8)
Give reasons for the sickling of RBC.
Decreased availability of O2 in blood
Mutations in the beta-globin genes
Excessive formation of HbA
Infection in malaria
Explanation
The sickling of RBC is caused by decreased O2 in blood or mutation in the beta-globin genes.
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