Essential Biochemistry - Chemistry Of Hemoglobin (Section 1 - No. 2)
What is the effect of high altitude on the binding of oxygen to hemoglobin?
Decreases the affinity of hemoglobin for oxygen
Increases the affinity of hemoglobin for oxygen.
Has no effect on oxygen binding.
Causes the hemoglobin to denature.
Explanation
At high altitudes, the increase in 2,3-BPG decreases the affinity of hemoglobin for oxygen.
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