Essential Biochemistry - Carbohydrate Metabolism (Section 4 - No. 41)

The activity of this enzyme is regulated by cellular concentrations of NADP+/NADPH in a competitive inhibition of the enzyme G-6-PD. An increased concentration of NADPH decreases the activity of G-6-PD. For example:
Under catabolic condition, the level of NADPH decreases and pentose phosphate pathway to stimulate.
Under anabolic condition, the level of NADPH decreases and pentose phosphate pathway to stimulate.
Under catabolic condition, the level of NADPH decreases and pentose phosphate pathway to stimulate.
Under anabolic condition, the level of NADPH increases and pentose phosphate pathway to stimulate.

Explanation

Under anabolic condition, the level of NADPH increases and pentose phosphate pathway to stimulate.

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