Quick Biochemistry - Nucleic Acids (Section 1)

  • 1
    What components combine to form a nucleoside?
    Хариулт
    (B)
    A purine or pyrimidine base and a sugar
  • 2
    Which of the following best describes the composition of a nucleotide?
    Хариулт
    (B)
    A purine and pyrimidine base, a sugar, and phosphorous
  • 3
    Which of the following is classified as a purine nucleotide?
    Хариулт
    (A)
    AMP
  • 4
    Which option represents a pyrimidine nucleotide?
    Хариулт
    (C)
    CMP
  • 5
    Adenine is also known as:
    Хариулт
    (A)
    6-Amino purine
  • 6
    What is the other name for 2, 4-Dioxypyrimidine?
    Хариулт
    (C)
    Uracil
  • 7
    What is the chemical designation for guanine?
    Хариулт
    (B)
    2-Amino-6-oxypurine
  • 8
    In what units are the concentrations of nucleotides and nucleic acids frequently expressed?
    Хариулт
    (D)
    OD at 260 nm
  • 9
    Which pyrimidine nucleotide is involved in high-energy intermediate reactions?
    Хариулт
    (C)
    UDPG
  • 10
    In a nucleotide, what carbon position on the pentose molecule is involved in an ester bond with phosphate?
    Хариулт
    (D)
    C₅
  • 11
    What molecule results from the combination of uracil and ribose?
    Хариулт
    (A)
    Uridine
  • 12
    Which nucleotide is most prevalent in a free state within animal cells?
    Хариулт
    (A)
    ATP
  • 13
    Approximately what is the average intracellular concentration of ATP in a mammalian cell?
    Хариулт
    (A)
    1 mM
  • 14
    Which base is present in messenger RNA but absent in deoxyribonucleic acid?
    Хариулт
    (D)
    Uracil
  • 15
    What is the function of 'Caps' in an RNA molecule?
    Хариулт
    (B)
    Are unique to eukaryotic mRNA
  • 16
    How does prokaryotic mRNA differ from eukaryotic mRNA?
    Хариулт
    (A)
    Can be polycistronic
  • 17
    What is the approximate size range of small stable RNA molecules?
    Хариулт
    (C)
    90-300 nucleotides
  • 18
    What is the approximate range of small stable RNAs found within a single cell?
    Хариулт
    (C)
    1,00,000-10,00,000
  • 19
    What is the approximate molecular weight of heterogenous nuclear RNA (hnRNA)?
    Хариулт
    (A)
    More than 107
  • 20
    In RNA, why isn't the guanine content always equal to cytosine, and adenine always equal to uracil?
    Хариулт
    (A)
    Single strand molecule
  • 21
    Which nitrogenous base is found in RNA?
    Хариулт
    (B)
    Uracil
  • 22
    Which of the following is NOT a component of RNA?
    Хариулт
    (C)
    Thymine
  • 23
    What type of sugar is found in RNA?
    Хариулт
    (C)
    Ribose
  • 24
    Which statement accurately describes base pairing in an RNA molecule?
    Хариулт
    (D)
    Guanine content does not necessarily equal its cytosine content.
  • 25
    In which type of RNA are methylated purines and pyrimidines typically found?
    Хариулт
    (C)
    tRNA
  • 26
    Where is Thymine typically found?
    Хариулт
    (A)
    tRNA
  • 27
    What is the approximate number of nucleotides in a tRNA molecule?
    Хариулт
    (C)
    75
  • 28
    In a typical cell, what is the minimum number of different tRNA molecules present?
    Хариулт
    (B)
    20
  • 29
    What shape does a tRNA molecule resemble?
    Хариулт
    (C)
    Clover leaf
  • 30
    In tRNA molecules, the CCA sequence is always located at the:
    Хариулт
    (A)
    3' Termini
  • 31
    What is the basis for classifying Transfer RNAs?
    Хариулт
    (D)
    Extra arm
  • 32
    Which modified base is found in the D arm of a tRNA molecule, giving it its name?
    Хариулт
    (A)
    Uridine
  • 33
    How many base pairs are typically found in the acceptor arm of a tRNA molecule?
    Хариулт
    (B)
    7 Base pairs
  • 34
    How many base pairs does the anticodon arm of a tRNA molecule typically possess?
    Хариулт
    (A)
    5 Base pairs
  • 35
    What sequence is typically found in the TΨC arm of a tRNA molecule?
    Хариулт
    (A)
    T, pseudouridine and C
  • 36
    Who put forth the double helical structure model of DNA?
    Хариулт
    (C)
    Watson and Crick
  • 37
    Which of the following is NOT found in DNA?
    Хариулт
    (C)
    Uracil
  • 38
    What is the type of sugar molecule found in DNA?
    Хариулт
    (A)
    Deoxyribose
  • 39
    DNA segments with a high concentration of A-T pairs are stabilized by how many hydrogen bonds?
    Хариулт
    (B)
    2 Hydrogen bonds
  • 40
    Which statement accurately describes the base composition in a DNA molecule?
    Хариулт
    (D)
    Guanine content equals cytosine content
  • 41
    DNA with a high proportion of G-C pairs tend to have what characteristic regarding hydrogen bonds?
    Хариулт
    (C)
    3 Hydrogen bonds
  • 42
    Given that DNA carries an organism's genetic code, what can be logically inferred about its base composition across different tissues?
    Хариулт
    (C)
    DNA from different tissues in the same organism should usually have the same base composition
  • 43
    What is the approximate width of the B-form DNA double helix in nanometers?
    Хариулт
    (B)
    2
  • 44
    How many base pairs are typically found in a single complete turn of the B-form DNA molecule?
    Хариулт
    (C)
    10
  • 45
    What is the distance, in nanometers, covered by one full turn of B-form DNA?
    Хариулт
    (D)
    3.4 nm
  • 46
    If the thymine concentration in a DNA molecule is 30%, what is the predicted concentration of guanosine?
    Хариулт
    (B)
    20%
  • 47
    If the guanosine content in a DNA molecule is 40%, what would be the percentage of adenine?
    Хариулт
    (A)
    10%
  • 48
    What factor leads to a higher melting temperature in duplex DNA?
    Хариулт
    (C)
    Cytosine + Guanine
  • 49
    What condition is often treated with the synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine?
    Хариулт
    (B)
    Gout
  • 50
    Which synthetic nucleotide analogue is frequently used in cancer and viral infection treatment?
    Хариулт
    (A)
    Arabinosyl cytosine