Quick Biochemistry - Hormone Metabolism (Section 1)

  • 1
    What is a function of hormones?
    Хариулт
    (C)
    Impact the production of enzymes
  • 2
    Which hormone interacts with receptors inside a cell?
    Хариулт
    (B)
    Thyroxine
  • 3
    Which hormone utilizes a cell surface receptor and cyclic AMP as a secondary messenger?
    Хариулт
    (A)
    Antidiuretic hormone
  • 4
    Which hormone originates from the anterior pituitary gland?
    Хариулт
    (A)
    Growth hormone
  • 5
    From which gland does vasopressin originate?
    Хариулт
    (A)
    Vasopressin
  • 6
    How many amino acids are in human growth hormone?
    Хариулт
    (C)
    191
  • 7
    What metabolic effect is caused by the increase in blood glucose due to growth hormone?
    Хариулт
    (A)
    Reduced use of glucose by tissues
  • 8
    What condition is caused by an overproduction of growth hormone?
    Хариулт
    (B)
    Growth hormone
  • 9
    Which substance triggers the release of growth hormone?
    Хариулт
    (B)
    Growth hormone releasing hormone
  • 10
    How many amino acids make up the prolactin molecule?
    Хариулт
    (D)
    199
  • 11
    A single polypeptide chain of Adrenocorticotropic hormone (ACTH) is composed of approximately how many amino acids?
    Хариулт
    (B)
    39
  • 12
    The effectiveness of ACTH in the body depends on which portion of its amino acid sequence?
    Хариулт
    (B)
    24-N-terminal amino acids
  • 13
    What hormones does ACTH primarily trigger the release of?
    Хариулт
    (A)
    Glucocorticoids
  • 14
    What medical condition is typically linked to an overproduction of ACTH?
    Хариулт
    (A)
    Cushing's syndrome
  • 15
    In the context of Cushing's syndrome, a condition associated with tumors in the adrenal cortex, what is a typical outcome?
    Хариулт
    (B)
    Excessive cortisol production
  • 16
    ACTH leads to an increase in which of the following substances?
    Хариулт
    (A)
    Cyclic AMP
  • 17
    What is the approximate ACTH concentration usually found circulating in the plasma?
    Хариулт
    (B)
    0.1-2.0 m μ/100 ml
  • 18
    What is the primary mechanism by which glucocorticoids elevate blood glucose levels?
    Хариулт
    (C)
    Stimulation of pyruvate carboxylase synthesis
  • 19
    Which of the following is the most common glucocorticoid present in the body?
    Хариулт
    (A)
    Cortisol
  • 20
    The protein primarily responsible for binding cortisol in the bloodstream, also known as transcortin, belongs to which protein group?
    Хариулт
    (C)
    α₂-Globulin
  • 21
    The specific location where cortisol is produced is the
    Хариулт
    (A)
    Zona fasiculata
  • 22
    All steroid hormones in mammals are derived from
    Хариулт
    (C)
    Cholesterol
  • 23
    A substance that effectively hinders the creation of steroid hormones is
    Хариулт
    (A)
    Aminoglutethimide
  • 24
    Within the adrenal gland, cholesterol is primarily stored in
    Хариулт
    (B)
    Mostly in esterified form
  • 25
    Aldosterone production takes place in the
    Хариулт
    (C)
    Zona glomerulosa
  • 26
    During cortisol synthesis, the correct order of the involved enzymes is
    Хариулт
    (A)
    Hydroxylase-dehydrogenase + isomerase - hydroxylase
  • 27
    A deficiency in which adrenal cortex process causes a lack of glucocorticoids and mineralocorticoids?
    Хариулт
    (C)
    C-21 hydroxylase deficiency
  • 28
    The enzyme complex 3-β-Hydroxysteroid dehydrogenase and A5,4 isomerase converts the weak androgen DHEA into
    Хариулт
    (A)
    Androstenedione
  • 29
    In a state of rest, the normal concentration of cortisol in plasma ranges from
    Хариулт
    (C)
    5.0-15.0 µg/100 ml
  • 30
    The primary function of aldosterone is to
    Хариулт
    (A)
    Increase the rate of tubular reabsorption of sodium
  • 31
    Which factor strongly encourages aldosterone secretion?
    Хариулт
    (C)
    High potassium levels
  • 32
    Within the renin-angiotensin system, which is the main hormone?
    Хариулт
    (C)
    Angiotensin II
  • 33
    What triggers the release of aldosterone?
    Хариулт
    (C)
    Angiotensin II
  • 34
    In the process of creating Angiotensin I, renin interacts with Angiotensinogen and cuts at the
    Хариулт
    (A)
    Leucine-leucine spot
  • 35
    Where are catecholamine hormones produced?
    Хариулт
    (A)
    Chromaffin cells in the adrenal medulla
  • 36
    What are catecholamine hormones chemically classified as?
    Хариулт
    (A)
    3, 4-Dihydroxy derivatives of phenylethylamine
  • 37
    What is the correct order of steps to transform tyrosine into epinephrine?
    Хариулт
    (A)
    Ring hydroxylation-decarboxylation-side chain hydroxylation-N-methylation
  • 38
    Which hormone is crucial for causing uterine muscles to contract during childbirth?
    Хариулт
    (C)
    Oxytocin
  • 39
    How many amino acids make up the hormone oxytocin?
    Хариулт
    (B)
    9
  • 40
    Vasopressin and oxytocin are not bound to proteins in circulation and have a brief lifespan in plasma, approximately how long?
    Хариулт
    (B)
    2-4 minutes
  • 41
    What triggers the process of melanogenesis?
    Хариулт
    (A)
    MSH
  • 42
    How many amino acids make up antidiuretic hormone?
    Хариулт
    (A)
    9
  • 43
    Which of the following actions is associated with ADH?
    Хариулт
    (A)
    Reabsorbs water from renal tubules
  • 44
    What is the primary result of the hormone's secretion that leads to increased water reabsorption in the kidney?
    Хариулт
    (C)
    Vasopressin
  • 45
    What effect does a rise in the osmolality of the extracellular space have?
    Хариулт
    (B)
    Stimulate ADH secretion
  • 46
    Which enzyme is the primary regulator in the creation of Catecholamines?
    Хариулт
    (C)
    Tyrosine hydroxylase
  • 47
    Which hormone is unable to pass through the barrier protecting the brain?
    Хариулт
    (A)
    Epinephrine
  • 48
    The concentration of epinephrine in plasma is typically below:
    Хариулт
    (A)
    0.1 ng/ml
  • 49
    How is epinephrine quickly broken down by the body?
    Хариулт
    (A)
    Monoamine oxidase
  • 50
    What bodily structure is the location of Pheochromocytomas tumors?
    Хариулт
    (B)
    Adrenal medulla