Essential Biochemistry - Enzymes (Section 5)

  • 1
    In feedback allosteric inhibition, the first enzyme of the sequence is inhibited by:
    Хариулт
    (B)
    The end product of the multienzyme system
  • 2
    Dilsulfiram is used to treat:
    Хариулт
    (A)
    Alcoholism
  • 3
    What is a key feature of how irreversible inhibitors interact with enzymes?
    Хариулт
    (B)
    They often form covalent bonds.
  • 4
    Which enzyme class is involved in the transfer of a group from one molecule to another?
    Хариулт
    (B)
    Transferases
  • 5
    Which of the following is NOT an example of a noncompetitive inhibitor?
    Хариулт
    (D)
    Aspirin
  • 6
    In the process of feedback inhibition, the inhibited enzyme is most frequently:
    Хариулт
    (C)
    The first enzyme in the pathway.
  • 7
    Asparin inactivates the enzyme:
    Хариулт
    (B)
    Cyclo-oxygenase
  • 8
    Which enzyme does DFP inhibit?
    Хариулт
    (A)
    Acetylcholine esterase
  • 9
    Asparaginase is used to treat which condition?
    Хариулт
    (B)
    Leukemia
  • 10
    DDT, an insecticide, is an example of a:
    Хариулт
    (C)
    Group-specific irreversible inhibitor.
  • 11
    Which of the following is a characteristic of reversible inhibitors?
    Хариулт
    A
    D
  • 12
    What is the primary function of DFP as an inhibitor?
    Хариулт
    (A)
    To inhibit Acetylcholinesterase
  • 13
    The target enzyme of aspirin is:
    Хариулт
    (A)
    Cyclooxygenase
  • 14
    DDT can be classified as which type of inhibitor?
    Хариулт
    (C)
    Group-specific irreversible inhibitor
  • 15
    Aspirin inactivates which enzyme?
    Хариулт
    (B)
    Cyclo-oxygenase
  • 16
    What type of inhibition is seen when the inhibitor has a structure similar to the substrate?
    Хариулт
    (A)
    Competitive Inhibition
  • 17
    Liver diagnostic enzyme is:
    Хариулт
    (C)
    Alanine transaminase
  • 18
    Dilsulfiram is used in the treatment of:
    Хариулт
    (A)
    Alcoholism
  • 19
    What is the role of cofactors in enzyme reactions?
    Хариулт
    (B)
    They directly participate in catalysis
  • 20
    Aspirin's main target is:
    Хариулт
    (A)
    Cyclooxygenase
  • 21
    Dilsulfiram is a drug used to treat alcoholism because it inhibits:
    Хариулт
    (B)
    Aldehyde dehydrogenase
  • 22
    What type of reaction is catalyzed by a hydrolase?
    Хариулт
    (A)
    Hydrolysis
  • 23
    The binding site of an allosteric regulator is:
    Хариулт
    (B)
    The allosteric site.
  • 24
    The enzyme useful in the treatment of leukemia is:
    Хариулт
    (B)
    Asparaginase
  • 25
    The primary mode of action for noncompetitive inhibitors involves:
    Хариулт
    (C)
    Binding to a site other than the active site, affecting Vmax.
  • 26
    Ethanol and certain anorexic drugs are examples of which type of inhibitor?
    Хариулт
    (B)
    Noncompetitive
  • 27
    Enzymes are used in which of the following?
    Хариулт
    A
    B
    C
    D
  • 28
    Group specific irreversible inhibitors target:
    Хариулт
    (A)
    Specific functional groups
  • 29
    Aspirin inhibits which enzyme?
    Хариулт
    (A)
    Cyclooxygenase
  • 30
    An elevated CK-MB level indicates:
    Хариулт
    (C)
    Cardiac muscle damage
  • 31
    Which of the following are used in the treatment of leukemia?
    Хариулт
    (A)
    Asparaginase
  • 32
    What happens to Km in the presence of a competitive inhibitor?
    Хариулт
    (A)
    Increases
  • 33
    In enzyme kinetics, Vmax represents:
    Хариулт
    (B)
    The maximum rate of an enzymatic reaction
  • 34
    Feedback inhibition regulates which component of the pathway?
    Хариулт
    (B)
    The first enzyme in the pathway
  • 35
    How do enzymes affect the equilibrium constant (Keq) of a reaction?
    Хариулт
    (C)
    They do not affect it
  • 36
    Noncompetitive inhibitors primarily impact enzyme function by:
    Хариулт
    (C)
    Binding elsewhere on the enzyme, changing Vmax.
  • 37
    In obstructive jaundice, which of the following enzyme levels typically increase?
    Хариулт
    B
    C
  • 38
    Enzymes may be used as the following, except:
    Хариулт
    (D)
    Nutrients
  • 39
    The analysis of certain plasma enzymes is primarily used for:
    Хариулт
    (A)
    Diagnostic purposes
  • 40
    Which of the following is used to treat leukemia?
    Хариулт
    (A)
    Asparaginase
  • 41
    Enzymes are biological catalysts that:
    Хариулт
    (A)
    Increase the rate of chemical reactions
  • 42
    The active site of an enzyme is the region that:
    Хариулт
    (C)
    Both binds and catalyzes the reaction
  • 43
    Which of the following is NOT a characteristic of enzymes?
    Хариулт
    (B)
    Require activation energy
  • 44
    Which of the following is an example of a physiological agent influencing enzyme activity?
    Хариулт
    A
    B
    D
  • 45
    The LDH1 tetramer is made of which polypeptide types?
    Хариулт
    (C)
    M and H
  • 46
    Enzymes are utilized for:
    Хариулт
    A
    B
    C
  • 47
    The allosteric effect involves binding at which site on the enzyme?
    Хариулт
    (B)
    Allosteric site
  • 48
    Dilsulfiram is used in the treatment of which condition?
    Хариулт
    (A)
    Alcoholism
  • 49
    The effect of dilsulfiram on aldehyde dehydrogenase leads to:
    Хариулт
    (B)
    Accumulation of acetaldehyde.
  • 50
    An enzyme can be used for:
    Хариулт
    A
    B
    C
    D