Quick Biochemistry - Nucleic Acids (Section 1)

  • 1
    What components combine to form a nucleoside?
    პასუხი
    (B)
    A purine or pyrimidine base and a sugar
  • 2
    Which of the following best describes the composition of a nucleotide?
    პასუხი
    (B)
    A purine and pyrimidine base, a sugar, and phosphorous
  • 3
    Which of the following is classified as a purine nucleotide?
    პასუხი
    (A)
    AMP
  • 4
    Which option represents a pyrimidine nucleotide?
    პასუხი
    (C)
    CMP
  • 5
    Adenine is also known as:
    პასუხი
    (A)
    6-Amino purine
  • 6
    What is the other name for 2, 4-Dioxypyrimidine?
    პასუხი
    (C)
    Uracil
  • 7
    What is the chemical designation for guanine?
    პასუხი
    (B)
    2-Amino-6-oxypurine
  • 8
    In what units are the concentrations of nucleotides and nucleic acids frequently expressed?
    პასუხი
    (D)
    OD at 260 nm
  • 9
    Which pyrimidine nucleotide is involved in high-energy intermediate reactions?
    პასუხი
    (C)
    UDPG
  • 10
    In a nucleotide, what carbon position on the pentose molecule is involved in an ester bond with phosphate?
    პასუხი
    (D)
    C₅
  • 11
    What molecule results from the combination of uracil and ribose?
    პასუხი
    (A)
    Uridine
  • 12
    Which nucleotide is most prevalent in a free state within animal cells?
    პასუხი
    (A)
    ATP
  • 13
    Approximately what is the average intracellular concentration of ATP in a mammalian cell?
    პასუხი
    (A)
    1 mM
  • 14
    Which base is present in messenger RNA but absent in deoxyribonucleic acid?
    პასუხი
    (D)
    Uracil
  • 15
    What is the function of 'Caps' in an RNA molecule?
    პასუხი
    (B)
    Are unique to eukaryotic mRNA
  • 16
    How does prokaryotic mRNA differ from eukaryotic mRNA?
    პასუხი
    (A)
    Can be polycistronic
  • 17
    What is the approximate size range of small stable RNA molecules?
    პასუხი
    (C)
    90-300 nucleotides
  • 18
    What is the approximate range of small stable RNAs found within a single cell?
    პასუხი
    (C)
    1,00,000-10,00,000
  • 19
    What is the approximate molecular weight of heterogenous nuclear RNA (hnRNA)?
    პასუხი
    (A)
    More than 107
  • 20
    In RNA, why isn't the guanine content always equal to cytosine, and adenine always equal to uracil?
    პასუხი
    (A)
    Single strand molecule
  • 21
    Which nitrogenous base is found in RNA?
    პასუხი
    (B)
    Uracil
  • 22
    Which of the following is NOT a component of RNA?
    პასუხი
    (C)
    Thymine
  • 23
    What type of sugar is found in RNA?
    პასუხი
    (C)
    Ribose
  • 24
    Which statement accurately describes base pairing in an RNA molecule?
    პასუხი
    (D)
    Guanine content does not necessarily equal its cytosine content.
  • 25
    In which type of RNA are methylated purines and pyrimidines typically found?
    პასუხი
    (C)
    tRNA
  • 26
    Where is Thymine typically found?
    პასუხი
    (A)
    tRNA
  • 27
    What is the approximate number of nucleotides in a tRNA molecule?
    პასუხი
    (C)
    75
  • 28
    In a typical cell, what is the minimum number of different tRNA molecules present?
    პასუხი
    (B)
    20
  • 29
    What shape does a tRNA molecule resemble?
    პასუხი
    (C)
    Clover leaf
  • 30
    In tRNA molecules, the CCA sequence is always located at the:
    პასუხი
    (A)
    3' Termini
  • 31
    What is the basis for classifying Transfer RNAs?
    პასუხი
    (D)
    Extra arm
  • 32
    Which modified base is found in the D arm of a tRNA molecule, giving it its name?
    პასუხი
    (A)
    Uridine
  • 33
    How many base pairs are typically found in the acceptor arm of a tRNA molecule?
    პასუხი
    (B)
    7 Base pairs
  • 34
    How many base pairs does the anticodon arm of a tRNA molecule typically possess?
    პასუხი
    (A)
    5 Base pairs
  • 35
    What sequence is typically found in the TΨC arm of a tRNA molecule?
    პასუხი
    (A)
    T, pseudouridine and C
  • 36
    Who put forth the double helical structure model of DNA?
    პასუხი
    (C)
    Watson and Crick
  • 37
    Which of the following is NOT found in DNA?
    პასუხი
    (C)
    Uracil
  • 38
    What is the type of sugar molecule found in DNA?
    პასუხი
    (A)
    Deoxyribose
  • 39
    DNA segments with a high concentration of A-T pairs are stabilized by how many hydrogen bonds?
    პასუხი
    (B)
    2 Hydrogen bonds
  • 40
    Which statement accurately describes the base composition in a DNA molecule?
    პასუხი
    (D)
    Guanine content equals cytosine content
  • 41
    DNA with a high proportion of G-C pairs tend to have what characteristic regarding hydrogen bonds?
    პასუხი
    (C)
    3 Hydrogen bonds
  • 42
    Given that DNA carries an organism's genetic code, what can be logically inferred about its base composition across different tissues?
    პასუხი
    (C)
    DNA from different tissues in the same organism should usually have the same base composition
  • 43
    What is the approximate width of the B-form DNA double helix in nanometers?
    პასუხი
    (B)
    2
  • 44
    How many base pairs are typically found in a single complete turn of the B-form DNA molecule?
    პასუხი
    (C)
    10
  • 45
    What is the distance, in nanometers, covered by one full turn of B-form DNA?
    პასუხი
    (D)
    3.4 nm
  • 46
    If the thymine concentration in a DNA molecule is 30%, what is the predicted concentration of guanosine?
    პასუხი
    (B)
    20%
  • 47
    If the guanosine content in a DNA molecule is 40%, what would be the percentage of adenine?
    პასუხი
    (A)
    10%
  • 48
    What factor leads to a higher melting temperature in duplex DNA?
    პასუხი
    (C)
    Cytosine + Guanine
  • 49
    What condition is often treated with the synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine?
    პასუხი
    (B)
    Gout
  • 50
    Which synthetic nucleotide analogue is frequently used in cancer and viral infection treatment?
    პასუხი
    (A)
    Arabinosyl cytosine