Essential Biochemistry - Connective Tissue (Section 2)

  • 1
    Which of the following amino acids is NOT typically found in collagen?
    პასუხი
    (D)
    Cysteine
  • 2
    What type of bond stabilizes the triple helix structure of collagen?
    პასუხი
    (B)
    Hydrogen bonds
  • 3
    Which of the following best describes the structure of elastin?
    პასუხი
    (C)
    Rubber-like protein
  • 4
    Collagen contents of helix destabilizing amino acid is:
    პასუხი
    (A)
    Glycine
  • 5
    What is the role of hyaluronic acid, chondroitin sulfate, and heparin in connective tissue?
    პასუხი
    (B)
    They are the major glycosaminoglycans
  • 6
    Where are the majority of elastin fibers found?
    პასუხი
    (D)
    Blood vessels
  • 7
    Hydroxylation of proline requires which of the following?
    პასუხი
    (D)
    All of the above
  • 8
    The basic subunit of elastic fibrils is:
    პასუხი
    (B)
    Tropoelastin
  • 9
    Which of the following are disorders of connective tissue?
    პასუხი
    A
    B
    D
  • 10
    Which enzyme is required for the cross-linking of collagen chains?
    პასუხი
    (B)
    Lysyl oxidase
  • 11
    What condition results from a deficiency in ascorbic acid (vitamin C)?
    პასუხი
    (B)
    Scurvy
  • 12
    Which type of cross-links stabilize the collagen fibril?
    პასუხი
    A
    C
    D
  • 13
    What is the primary genetic defect in osteogenesis imperfecta?
    პასუხი
    (C)
    Multiple genetic defects in type-I collagen synthesis
  • 14
    Which of the following is not a genetic disorder of collagen?
    პასუხი
    (C)
    Scurvy
  • 15
    A deficiency of copper affects the formation of normal collagen by reducing the activity of:
    პასუხი
    (B)
    Lysyl oxidase