Essential Biochemistry - Cancer (Section 2)

  • 1
    Which of the following is an example of an oncofetal antigen?
    Respuesta
    (B)
    CEA
  • 2
    Activation of proto-oncogenes to oncogenes occur by following mechanisms, except:
    Respuesta
    (D)
    Post-translational modification
  • 3
    Which of the following is NOT a step in the development of cancer?
    Respuesta
    (D)
    Replication
  • 4
    Which of the following is an example of a direct-acting carcinogen?
    Respuesta
    (C)
    Cyclophosphamide
  • 5
    Which of the following is an example of an inorganic carcinogen?
    Respuesta
    (A)
    Asbestos
  • 6
    What does the term "metastasis" refer to in the context of cancer?
    Respuesta
    (C)
    Spread of cancer to other parts of the body
  • 7
    What type of radiation causes DNA damage?
    Respuesta
    A
    B
  • 8
    Which dietary component is associated with a reduced risk of cancer?
    Respuesta
    (C)
    High fiber intake
  • 9
    Genes capable of causing cancer are, except:
    Respuesta
    (D)
    Antioncogenes
  • 10
    What is the term for cancer that spreads to other parts of the body?
    Respuesta
    (B)
    Metastasis
  • 11
    Which of the following is a characteristic of transformed cells?
    Respuesta
    (D)
    Loss of contact inhibition of growth
  • 12
    What are the two main types of carcinogenic viruses?
    Respuesta
    (A)
    RNA and DNA oncogenic viruses
  • 13
    What is a proto-oncogene?
    Respuesta
    (A)
    A normal gene that can become an oncogene
  • 14
    What is the main source of UV radiation?
    Respuesta
    (B)
    Sunlight
  • 15
    Which of the following is the term for a substance or agent that can cause cancer?
    Respuesta
    (C)
    Carcinogen
  • 16
    Which of the following is an example of a chemical carcinogen?
    Respuesta
    (C)
    Benzo[a]pyrene
  • 17
    Which of the following are associated with cancer cells?
    Respuesta
    A
    B
    C
  • 18
    Tumor suppressor genes are sometimes called:
    Respuesta
    (A)
    Antioncogenes
  • 19
    What type of cell division is often inhibited in cancer cells?
    Respuesta
    (A)
    Apoptosis
  • 20
    What is the role of a proto-oncogene?
    Respuesta
    (A)
    To stimulate cell division
  • 21
    Which of the following statements is correct concerning the origin of cancers?
    Respuesta
    (C)
    Cancers can originate from various tissues and cell types
  • 22
    Which of the following is NOT a type of cancer according to its tissue/cell of origin?
    Respuesta
    (D)
    Pneumonia
  • 23
    Carcinogens are classified into:
    Respuesta
    (A)
    Chemical, physical and biological
  • 24
    Which of the following is a characteristic of cancer cells?
    Respuesta
    (D)
    Loss of differentiation
  • 25
    What process does the action of chemical carcinogens leads to?
    Respuesta
    (A)
    Mutation in DNA
  • 26
    Which of the following is an example of a promoter of carcinogenesis?
    Respuesta
    (B)
    Phenobarbital
  • 27
    Which of the following compounds is associated with cancer risk in food?
    Respuesta
    (A)
    Nitrosamine
  • 28
    What do retroviruses contain which can cause alterations in cell gene expression and cause cancer?
    Respuesta
    (B)
    RNA
  • 29
    Which of the following is/are the ways tumor markers can be used?
    Respuesta
    (D)
    All of the above
  • 30
    What type of gene, when mutated, can lead to cancer by stimulating cell division?
    Respuesta
    (B)
    Proto-oncogene
  • 31
    The spread of cancer cells to other parts of the body is called:
    Respuesta
    (C)
    Metastasis
  • 32
    Which of the following are characteristics of cancer cells?
    Respuesta
    A
    B
    C
  • 33
    Which of the following are examples of indirect acting carcinogens?
    Respuesta
    B
    D
  • 34
    Which of the following is a type of tumor marker?
    Respuesta
    (D)
    All of the above
  • 35
    What type of agent can be used to initiate the process of abnormal cell growth?
    Respuesta
    (B)
    Carcinogens
  • 36
    What are the two subgroups of initiators of carcinogenesis?
    Respuesta
    (A)
    Initiators and Promoters
  • 37
    What is the term for the loss of growth control in cancer cells?
    Respuesta
    (B)
    Unrestricted growth
  • 38
    What is the main source of UV radiation?
    Respuesta
    (C)
    Sunlight
  • 39
    Which of the following are examples of RNA oncogenic viruses?
    Respuesta
    (D)
    All of the above
  • 40
    Which of the following is associated with an increased risk of colon cancer?
    Respuesta
    (C)
    Increased nitrosamine consumption
  • 41
    Which of the following is an example of a DNA oncogenic virus?
    Respuesta
    (B)
    Herpes viruses
  • 42
    The main source of UV radiation is:
    Respuesta
    (B)
    Sunlight
  • 43
    Which of the following is a characteristic of cancer cells related to growth?
    Respuesta
    (C)
    Unrestricted growth
  • 44
    Which of the following is NOT a carbohydrate tumor marker?
    Respuesta
    (D)
    CEA
  • 45
    Which of the following diet types increases the risk of cancer?
    Respuesta
    (C)
    High fat and animal protein diet
  • 46
    Which of the following are directly involved in the process of carcinogenesis?
    Respuesta
    A
    B
    C
    D
  • 47
    Which of the following statements is true regarding tumor markers?
    Respuesta
    (C)
    They can be used to monitor the progression of cancer.
  • 48
    What is the role of a tumor suppressor gene?
    Respuesta
    (B)
    Inhibit cell division
  • 49
    What is a proto-oncogene?
    Respuesta
    (B)
    A normal gene that can become an oncogene
  • 50
    Which of the following is an example of an indirect-acting carcinogen?
    Respuesta
    (C)
    Benzo[a]pyrene