Quick Biochemistry - Nucleic Acids (Section 1)

  • 1
    What components combine to form a nucleoside?
    إجابة
    (B)
    A purine or pyrimidine base and a sugar
  • 2
    Which of the following best describes the composition of a nucleotide?
    إجابة
    (B)
    A purine and pyrimidine base, a sugar, and phosphorous
  • 3
    Which of the following is classified as a purine nucleotide?
    إجابة
    (A)
    AMP
  • 4
    Which option represents a pyrimidine nucleotide?
    إجابة
    (C)
    CMP
  • 5
    Adenine is also known as:
    إجابة
    (A)
    6-Amino purine
  • 6
    What is the other name for 2, 4-Dioxypyrimidine?
    إجابة
    (C)
    Uracil
  • 7
    What is the chemical designation for guanine?
    إجابة
    (B)
    2-Amino-6-oxypurine
  • 8
    In what units are the concentrations of nucleotides and nucleic acids frequently expressed?
    إجابة
    (D)
    OD at 260 nm
  • 9
    Which pyrimidine nucleotide is involved in high-energy intermediate reactions?
    إجابة
    (C)
    UDPG
  • 10
    In a nucleotide, what carbon position on the pentose molecule is involved in an ester bond with phosphate?
    إجابة
    (D)
    C₅
  • 11
    What molecule results from the combination of uracil and ribose?
    إجابة
    (A)
    Uridine
  • 12
    Which nucleotide is most prevalent in a free state within animal cells?
    إجابة
    (A)
    ATP
  • 13
    Approximately what is the average intracellular concentration of ATP in a mammalian cell?
    إجابة
    (A)
    1 mM
  • 14
    Which base is present in messenger RNA but absent in deoxyribonucleic acid?
    إجابة
    (D)
    Uracil
  • 15
    What is the function of 'Caps' in an RNA molecule?
    إجابة
    (B)
    Are unique to eukaryotic mRNA
  • 16
    How does prokaryotic mRNA differ from eukaryotic mRNA?
    إجابة
    (A)
    Can be polycistronic
  • 17
    What is the approximate size range of small stable RNA molecules?
    إجابة
    (C)
    90-300 nucleotides
  • 18
    What is the approximate range of small stable RNAs found within a single cell?
    إجابة
    (C)
    1,00,000-10,00,000
  • 19
    What is the approximate molecular weight of heterogenous nuclear RNA (hnRNA)?
    إجابة
    (A)
    More than 107
  • 20
    In RNA, why isn't the guanine content always equal to cytosine, and adenine always equal to uracil?
    إجابة
    (A)
    Single strand molecule
  • 21
    Which nitrogenous base is found in RNA?
    إجابة
    (B)
    Uracil
  • 22
    Which of the following is NOT a component of RNA?
    إجابة
    (C)
    Thymine
  • 23
    What type of sugar is found in RNA?
    إجابة
    (C)
    Ribose
  • 24
    Which statement accurately describes base pairing in an RNA molecule?
    إجابة
    (D)
    Guanine content does not necessarily equal its cytosine content.
  • 25
    In which type of RNA are methylated purines and pyrimidines typically found?
    إجابة
    (C)
    tRNA
  • 26
    Where is Thymine typically found?
    إجابة
    (A)
    tRNA
  • 27
    What is the approximate number of nucleotides in a tRNA molecule?
    إجابة
    (C)
    75
  • 28
    In a typical cell, what is the minimum number of different tRNA molecules present?
    إجابة
    (B)
    20
  • 29
    What shape does a tRNA molecule resemble?
    إجابة
    (C)
    Clover leaf
  • 30
    In tRNA molecules, the CCA sequence is always located at the:
    إجابة
    (A)
    3' Termini
  • 31
    What is the basis for classifying Transfer RNAs?
    إجابة
    (D)
    Extra arm
  • 32
    Which modified base is found in the D arm of a tRNA molecule, giving it its name?
    إجابة
    (A)
    Uridine
  • 33
    How many base pairs are typically found in the acceptor arm of a tRNA molecule?
    إجابة
    (B)
    7 Base pairs
  • 34
    How many base pairs does the anticodon arm of a tRNA molecule typically possess?
    إجابة
    (A)
    5 Base pairs
  • 35
    What sequence is typically found in the TΨC arm of a tRNA molecule?
    إجابة
    (A)
    T, pseudouridine and C
  • 36
    Who put forth the double helical structure model of DNA?
    إجابة
    (C)
    Watson and Crick
  • 37
    Which of the following is NOT found in DNA?
    إجابة
    (C)
    Uracil
  • 38
    What is the type of sugar molecule found in DNA?
    إجابة
    (A)
    Deoxyribose
  • 39
    DNA segments with a high concentration of A-T pairs are stabilized by how many hydrogen bonds?
    إجابة
    (B)
    2 Hydrogen bonds
  • 40
    Which statement accurately describes the base composition in a DNA molecule?
    إجابة
    (D)
    Guanine content equals cytosine content
  • 41
    DNA with a high proportion of G-C pairs tend to have what characteristic regarding hydrogen bonds?
    إجابة
    (C)
    3 Hydrogen bonds
  • 42
    Given that DNA carries an organism's genetic code, what can be logically inferred about its base composition across different tissues?
    إجابة
    (C)
    DNA from different tissues in the same organism should usually have the same base composition
  • 43
    What is the approximate width of the B-form DNA double helix in nanometers?
    إجابة
    (B)
    2
  • 44
    How many base pairs are typically found in a single complete turn of the B-form DNA molecule?
    إجابة
    (C)
    10
  • 45
    What is the distance, in nanometers, covered by one full turn of B-form DNA?
    إجابة
    (D)
    3.4 nm
  • 46
    If the thymine concentration in a DNA molecule is 30%, what is the predicted concentration of guanosine?
    إجابة
    (B)
    20%
  • 47
    If the guanosine content in a DNA molecule is 40%, what would be the percentage of adenine?
    إجابة
    (A)
    10%
  • 48
    What factor leads to a higher melting temperature in duplex DNA?
    إجابة
    (C)
    Cytosine + Guanine
  • 49
    What condition is often treated with the synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine?
    إجابة
    (B)
    Gout
  • 50
    Which synthetic nucleotide analogue is frequently used in cancer and viral infection treatment?
    إجابة
    (A)
    Arabinosyl cytosine